June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene therapy in mice increased lifespan and improved health without causing cancer.
124 citations
,
April 2000 in “Nature biotechnology” 49 citations
,
March 2017 in “PubMed” Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
17 citations
,
January 2007 in “Annals of Medicine” Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.
January 2008 in “Vestnik Tomskogo gosudarstvennogo universiteta Filologiya” Overexpressing the Tβ4 gene in goats can increase cashmere production.
The protein's size was reduced, but more work is needed to confirm its function.
January 2004 in “Chinese Journal of Dermatology” Injecting specific oligonucleotides can change hair growth and structure by altering a gene.
4 citations
,
January 2014 in “BioMed Research International” Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
January 2009 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” Identifying and manipulating key genes can improve wool quality and productivity in sheep.
10 citations
,
January 2014 in “Journal of prosthodontic research” Bioengineered salivary glands in mice can produce saliva when tasting sour or bitter, but have different protein levels and nerve signals compared to natural glands.