research Alopezien und Hypotrichosen im Kindesalter
Genetic testing can identify causes of rare hair loss disorders in children, but no treatments exist.
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research Skin manifestations of Bardet–Biedl syndrome
Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.
research Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin
Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
research Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma
Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
research Dermatological diseases from a genetic perspective
New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
research Alopecia areata. Diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 1. Diagnosis and severity assessment
There are two main types of alopecia areata with different severity, and diagnosis is made through clinical examination and trichoscopy, influencing treatment choices.
research Managing patterned hair loss – a hair raising task!
Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
research 089 Neoplasms bypass immune evasion via hair follicle residence
Neoplasms hide in hair follicles to avoid the immune system.
research The therapeutic progress of androgenetic alopecia
Various treatments can help manage hair loss in androgenetic alopecia.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research A Perspective on RNAi-Based Biopesticides
RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
research Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: Studies on the natural history of the defect and effect of androgens on gender role
Individuals with this condition often develop male traits and identities at puberty despite being raised as females.
research Saccharomyces cerevisiae BLYAS, a New Bioluminescent Bioreporter for Detection of Androgenic Compounds
The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Alopecia areata and the gut—the link opens up for novel therapeutic interventions
Gut health may influence Alopecia Areata, suggesting new treatments.
research CRISPR/Cas9‐mediated loss of FGF5 function increases wool staple length in sheep
Disabling the FGF5 gene in sheep leads to longer wool.
research Genetics and other factors in the aetiology of female pattern hair loss
Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
research Food Deprivation-induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis
Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
research Enzymology of the hair follicle.
Hair follicles convert androgens, affecting hair loss patterns.
research Rare and common genetic determinants of metabolic individuality and their effects on human health
Genetic variations greatly affect individual metabolism and can impact health and disease risk.
research Current understanding of androgenetic alopecia. Part I: etiopathogenesis.
Androgenetic alopecia is common hair loss due to genetics and DHT.
research M2 macrophages promote wound-induced hair neogenesis
M2 macrophages, a type of immune cell, help in new hair growth on scars by producing growth factors.
research Enzyme Typing of Human Hair Roots
Enzyme typing can reliably characterize human hair.
research The extracellular matrix dictates regional competence for tumour initiation
The extracellular matrix affects where tumors can start in the body.
research Exogenous stimulation with Eclipta alba promotes hair matrix keratinocyte proliferation and downregulates TGF-β1 expression in nude mice
Eclipta alba extract helps increase hair growth and decrease hair loss-related protein in mice.
research Activating β-catenin signaling in CD133-positive dermal papilla cells increases hair inductivity
Boosting β-catenin signaling in certain skin cells can enhance hair growth.
research Treatment of Alopecia Areata with Anti-Interferon-γ Antibodies
Blocking interferon-gamma helps prevent and treat hair loss in Alopecia Areata.
research [Hormonal interaction and hair growth].
Hormones, especially DHT, affect hair loss and growth, and targeting specific enzymes may help treat hair loss.
research Overexpression of alkaline phosphatase improves the hair-inductive capacity of cultured human dermal papilla spheres
Increasing alkaline phosphatase in human skin cells helps to grow more hair.