25 citations
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April 2015 in “Journal of Investigative Dermatology” GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.
18 citations
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December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
5 citations
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September 2015 in “PubMed” Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
1 citations
,
March 2014 in “TURKDERM” Understanding hair follicles can lead to new treatments for hair loss and skin tumors.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
3 citations
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February 2017 in “Archives of Medical Science” Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
1066 citations
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March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
333 citations
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
150 citations
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December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
69 citations
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January 2013 in “Frontiers in Immunology” The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
51 citations
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July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
32 citations
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May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
27 citations
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September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
10 citations
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May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
January 2020 in “Research Portal Denmark” A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.
236 citations
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July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
151 citations
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November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
35 citations
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July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
1 citations
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August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
610 citations
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April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
143 citations
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September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
127 citations
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January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
75 citations
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September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.