5 citations
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December 2020 in “Gene” ANXA1 influences hair growth in mice through the EGF signaling pathway.
9 citations
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November 2021 in “Current Opinion in Genetics & Development” Wounds can cause new hair growth in adult mice, influenced by Wnt signaling.
4 citations
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May 2025 in “Cells” miR-370-3p slows sheep hair cell growth by blocking SMAD4.
January 2025 in “Antioxidants” SHED-CM can reduce hair graying and protect against damage from X-rays.
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
87 citations
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
43 citations
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December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
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June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
January 2013 in “Kidney international” A man with kidney tumors and lung cysts was diagnosed with Birt–Hogg–Dubé syndrome and treated successfully, with genetic testing confirming the diagnosis.
2 citations
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September 2020 in “International Journal of Molecular Sciences” Removing certain hair follicle stem cells worsens skin reactions to allergens.
January 2025 in “PLoS ONE” Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
222 citations
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August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
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May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
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February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
October 2025 in “Gene Expression” Exosome therapy could be a promising new way to treat hair loss.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
3 citations
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April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
March 2026 in “Cell Death Discovery” Targeting the p63 gene could help treat skin diseases.
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February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
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April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
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June 2021 in “Biomolecules & Therapeutics” Activating δ-opioid receptors can help hair grow.
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February 2011 in “Cell stem cell” COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.
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October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
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March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
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December 2023 in “Biomolecules” Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
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March 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
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January 2018 in “Stem cell biology and regenerative medicine” DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
September 2025 in “PubMed” Mechanical stimulation and new therapies show promise for hair regrowth.
February 2023 in “Vaccines” COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.