research Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro
Wharton's jelly stem cells show diverse traits and functions.
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research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma
research Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation
Meis2 is essential for whisker development, independent of nerve involvement.
research A SUBPOPULATION OF ITCH RECEPTORS MARKED BY RET EXPRESSION
A new type of nerve cell involved in itch perception was discovered.
research GRANULOSA‐THECA CELL TUMOR IN A ONE‐YEAR‐OLD INFANT
A rare ovarian tumor caused early puberty signs in a 1-year-old girl, but surgery reduced hormone levels.
research A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11
Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.
research Distinct fibroblast lineages determine dermal architecture in skin development and repair
Two fibroblast types shape skin structure and repair differently.
research Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle.
Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs
Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
research Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors
The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.
research Molecular mechanisms of asymmetric divisions in mammary stem cells
Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
research Mesenchymal Stem Cells With Modification of Junctional Adhesion Molecule A Induce Hair Formation
Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.
research Immunohistochemical Expression of the ${\alpha}$ - and ${\gamma}$ -catenin in the Fetal Skin Development
α- and γ-catenins help develop fetal skin by 23 weeks.
research Development of Heritable Melanoma in Transgenic Mice
The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
research Stem cell niche: from concept to reality
Stem cell niches are crucial for maintaining stem cells, with Paneth cells and TGF-beta playing key roles.
research Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models
New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
research 591 A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
research EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals
EGFR signaling is essential for ear cell regeneration in both birds and mammals.
research The organization of the keratin I and II gene clusters in placental mammals and marsupials show a striking similarity
Keratin gene clusters in humans and marsupials are similarly organized.
research Promotion of Hair Growth by Conditioned Medium from Extracellular Matrix/Stromal Vascular Fraction Gel in C57BL/6 Mice
A substance from a specific gel helped to grow hair effectively in mice, suggesting it could potentially be used to treat hair loss in humans.
research T-Regulating Hair Follicle Stem Cells
Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
research Np63 Regulates Stem Cell Dynamics in the Mammalian Olfactory Epithelium
p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
research Using High-Throughput Immunoblotting to Identify Proteins Involved in the Differentiation of ES Cells along the Hair Follicle Lineage in Vitro
The research helps understand how stem cells turn into hair follicle cells.
research Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer
TGM3 is important for skin and hair structure and may help diagnose cancer.
research The stiffness of the extracellular matrix is a key factor in tumor progression
Extracellular matrix stiffness affects how aggressively cancer cells invade.
research Postnatal determinants of testicular germ cell tumor by histological subtypes: The EPSAM1 and EPSAM2 studies
Childhood and adult height, and early immune-related hospitalizations increase testicular cancer risk, while baldness, larger families, and sports reduce it.
research Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle
Sox10 is important for hair follicle development and hair growth cycles.
research Notes from the Editor Emeritus
Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
research Differention of ES cell-derived epidermal stem cells in full thickness skin defects
ES cell-derived stem cells can help regenerate skin and form gland-like structures.