53 citations
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June 1983 in “Journal of Investigative Dermatology” The enzyme is crucial for skin cell development and can be activated without proteolytic activation.
13 citations
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July 2017 in “Biopolymers” Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.
7 citations
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July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
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January 2021 in “ScienceAsia” Using an enzyme and keratin treatment can significantly repair and strengthen damaged hair.
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January 2004 in “Genomics” A cluster of 21 keratin-associated protein genes important for hair growth was found on human chromosome 21.
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June 2022 in “Experimental dermatology” The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.
January 1999 in “Chinses Journal of Hand Surgery” Human hair keratin artificial tendon is a safe and effective tendon substitute.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created a detailed map of gene activity in different parts of human hair follicles.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The N-K GM Series offers treatments for full hair restoration and permanent hair removal, claiming 100% effectiveness without side effects.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The N-K GM Series offers treatments for full hair restoration and permanent hair removal, claiming 100% effectiveness without side effects.
April 2017 in “Journal of Investigative Dermatology” Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
194 citations
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May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
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November 2019 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
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February 1989 in “Journal of Investigative Dermatology” 11 citations
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January 1997 in “Journal of Dermatological Science” A new protein linked to hair strength was identified, aiding in understanding brittle hair conditions.
October 2021 in “Journal of Investigative Dermatology” Dkk4 protein is necessary for the proper development and arrangement of hair follicles.
March 2016 in “Experimental Dermatology” EGFR helps hair follicles transition properly by controlling Stathmin levels.
Giant axonal neuropathy changes the structure of keratin in human hair, making it stiffer and stronger.
1 citations
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November 2024 in “EMBO Reports” Deleting Gpr54 speeds up hair growth and regeneration.
53 citations
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October 2003 in “Genetics” The mK6irs1/Krt2-6g gene likely causes wavy hair in mice.
January 2000 in “Acta Academiae Medicine Militaris Tertiae” Different keratins in hair follicles can help identify hair tumor origins.
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March 2004 in “Journal of Investigative Dermatology” 2 citations
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January 2020 in “Benha Journal of Applied Sciences” 8-OHdG may help diagnose and assess alopecia areata.
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January 1977 in “PubMed” The hair keratin variant is mostly found in Caucasians.
April 2016 in “Journal of Investigative Dermatology” Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.
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January 2010 in “Human Molecular Genetics” FTase and GGTase-I are essential for skin keratinocyte health.
A new hydrogel made from human hair keratin can help regenerate skin and fight bacteria.
106 citations
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December 2015 in “Biomacromolecules” Keratin hydrogels can be customized for better tissue healing.
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April 2004 in “Journal of Investigative Dermatology” A new mouse gene, Keratin 17n, is mainly found in nail tissue and may explain why mice without Keratin 17 don't have nail issues.
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May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.