506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
57 citations
,
February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
1 citations
,
February 2023 in “International Journal of Molecular Sciences” Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.
26 citations
,
February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
8 citations
,
August 2020 in “Domestic Animal Endocrinology” Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.
July 2024 in “Journal of Investigative Dermatology” Topical melatonin may reduce skin aging by inhibiting certain cellular pathways.
15 citations
,
January 2023 in “Journal of Translational Autoimmunity” Melatonin may help treat skin conditions.
4 citations
,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
TrichoSol™ effectively stabilizes various hair treatment ingredients for different durations.
May 2024 in “International journal of molecular sciences” Melatonin cream may help prevent skin damage but its anti-aging and hair growth effects are unclear.
March 2025 in “International Journal of Molecular Sciences” Melatonin promotes hair growth and quality by enhancing hair follicle development and reducing stress.
April 2020 in “Research Square (Research Square)” Melatonin treatment improved cashmere production in goats for one cycle without lasting effects on the next cycle.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
3 citations
,
September 2022 in “Veterinary Dermatology” Melatonin implants did not effectively prevent hair loss in dogs.
40 citations
,
July 2018 in “European Journal of Pharmaceutical Sciences” Melatonin vitamin C-based nanovesicles improved hair growth and reduced hair loss in androgenic alopecia patients.
December 2023 in “International journal of high dilution research” Melatonin and Lissotriton improved hair quality and increased activity in mice.
46 citations
,
March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
122 citations
,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
44 citations
,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
January 2026 in “AAPS PharmSciTech” Liposomal formulations with caffeine and cafestol enhance skin penetration effectively.
61 citations
,
January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
April 2023 in “Journal of Investigative Dermatology” Cinchona succirubra extract with caffeine improves hair growth and reduces hair loss.
32 citations
,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
August 2025 in “Journal of Cosmetic Dermatology” The shampoo with DMG-Na and caffeine effectively reduces hair loss and improves hair density in men.
June 2008 in “Experimental dermatology” Melatonin protects skin and hair from damage and stress by acting as an antioxidant and influencing cell growth.
Melatonin helps hair grow.
222 citations
,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
3 citations
,
October 1996 in “International Journal of Dermatology” Melatonin can affect skin color, treat skin conditions, and may help with skin cancer.
7 citations
,
July 2018 in “International Journal of Applied Pharmaceutics” Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.