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Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Certain genes are linked to type 1 and type 2 diabetes in kids, and changes in these genes can also cause other diabetes-related conditions.

The LTF gene may help predict and manage nonspecific orbital inflammation.

Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

A 589 nm laser increases IL-2 and IFN-y gene expression in human T-cells.

Lgr5 and the vitamin D receptor are key in controlling skin inflammation and tumor risk in mice.

The 4C32 gene may help in mouse skin development and differentiation.

Phospholipase A2 enzymes play key roles in skin health and disease.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

FGF13 gene changes cause excessive hair growth in a rare condition.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Seven genes are highly expressed in both germ-line and hematopoietic stem cells.

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.

miRNAs in the Dlk1-Gtl2 region may improve lamb fur quality.

Non-coding RNAs may be key in diagnosing and treating rare skin disorders.

Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

PLIN2 affects hair growth in cashmere goats, potentially improving cashmere quality.

New LSS gene variants help understand congenital hypotrichosis 14 better.

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

PDGFC gene may help select goats with desirable curly wool traits.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.

KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.

The ID2 gene can help distinguish between sensitizers and irritants in skin cells.

Vitamin D and glucocorticoids affect bone growth, metabolism, and immune response.

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

Glucocorticoid receptors help regulate genes important for skin health and hair growth.

Genetic testing can diagnose hair loss linked to DSG4 gene variants.