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Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Excess androgens may cause PCOS, not just be a symptom.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

SGLT2 inhibitors may help manage PCOS symptoms effectively.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Liquorice has medicinal benefits, including antioxidant, anti-inflammatory, antimicrobial, antiulcer, and antiviral effects.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Stress increases neurosteroids that help prevent seizures.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Men with male pattern baldness had higher body fat and obesity-related measurements but similar heart fat and artery thickness compared to healthy men.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

DHEA supplementation may improve quality of life, neuropsychological functions, and sexual satisfaction in individuals with adrenal insufficiency, but more research is needed to confirm its safety and effectiveness.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Gut bacteria affect female reproductive health and may help diagnose and treat related diseases.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.