research Raising threshold for diagnosis of polycystic ovary syndrome excludes population of patients with metabolic risk
Changing the diagnosis criteria for PCOS might miss women at risk for related health issues.
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research Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing
A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
research Metabolic dysfunction in obese Hispanic women with polycystic ovary syndrome
Obese Hispanic women with PCOS are at higher risk for metabolic problems than non-Hispanic white women.
research Progestogens in menopausal hormone therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research Can serum vaspin levels predict clomiphene resistance in infertile women with PCOS?
Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.
research Inflammatory markers and Lp(a) levels as cardiovascular risk factors in androgenetic alopecia
AGA patients have higher heart disease risk.
research Cardiometabolic and neuroimaging correlates of cognitive function in polycystic ovary syndrome
Women with PCOS have altered brain structure and reduced cognitive performance.
research Retinol-binding protein 4, leptin, and insulin resistance in idiopathic hirsutism and hirsute women with polycystic ovary syndrome
Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.
research Cardiovascular and Metabolic Risk Profiles Across Different Phenotypes of Polycystic Ovary Syndrome
Women with PCOS have higher cardiometabolic risks.
research Inositol versus Metformin administration in polycystic ovary syndrome patients
Inositol was more effective than Metformin in treating symptoms of PCOS in women.
research Inositol versus metformin administration in polycystic ovarian disease patients
Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.
research Insulin Resistance and Polycystic Ovary Syndrome
Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia
Finasteride effectively treats BPH but may increase sexual dysfunction risk.
research Potential role and therapeutic interests of myo-inositol in metabolic diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research The pathophysiology of polycystic ovary syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Comparative Proteomics Indicates That Biosynthesis of Pectic Precursors Is Important for Cotton Fiber and Arabidopsis Root Hair Elongation
Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.
research Hirsutism and acne in polycystic ovary syndrome
Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.
research Endothelial Dysfunction in PCOS: Role of Obesity and Adipose Hormones
Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Adult polycystic ovary syndrome begins in childhood
Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.
research Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Potassium channel openers: pharmacological and clinical aspects
Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth
Activating TRPV3 stops human hair growth.
research FGF Family: From Drug Development to Clinical Application
FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
research Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp
The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
research Pharmacology of antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Minoxidil: a review of its pharmacological properties and therapeutic use.
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.