research Expression of NAD+dependent 15-hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle
A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
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research Androgen receptor modulators: a review of recent patents and reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research C57BL/6N 생쥐에서 골쇄보(骨碎補) 추출물을 이용한 발모(發毛)효과에 대한 실험적 연구
Drynariae Rhizoma extracts, especially the acetone and EtoAc fractions, may help treat hair loss.
research The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene
A new gene variant causes glucocorticoid resistance in a mother and son.
research Next Generation Therapeutics for Androgenetic Alopecia
This paper introduces a comprehensive therapeutic framework for androgenetic alopecia (AGA) that combines PROTAC-mediated androgen receptor (AR) degradation with regenerative and micro-environmental strategies. It highlights GT20029 as a topical AR-PROTAC and compares AR degradation with antagonism. The study also explores early-intervention models based on genetic predisposition and pre-miniaturization biomarkers. The framework integrates stem-cell biology, dermal papilla senescence, perifollicular fibrosis, and niche-engineering into a three-phase protocol: stabilization, reversal, and maintenance. Additionally, it proposes a development timeline for therapies and testable hypotheses to guide future research and clinical applications in AGA.
research Nephrogenic systemic fibrosis: Report of two cases
The document concludes that using gadolinium-based contrast agents during MRI can be linked to Nephrogenic Systemic Fibrosis in patients with severe kidney disease.
research D’orenone blocks polarized tip growth of root hairs by interfering with the PIN2‐mediated auxin transport network in the root apex
D'orenone stops root hair growth by disrupting auxin transport, but adding auxin can reverse this.
research Delayed granulomatous eruption of the nose associated with ruxolitinib
Ruxolitinib can cause a delayed skin reaction on the nose.
research Evaluation of the safety and effectiveness of intradermal administration of QR678 Neo® hair growth factor formulation: A phase‐IV, open‐label, single‐arm multi‐ethnicity clinical trial
QR678 Neo® is a safe and effective treatment for hair loss in men and women.