1 citations
,
February 2016 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.
April 2019 in “Journal of the Endocrine Society” The study found that imaging might miss small ovarian tumors causing high testosterone, and suggested using certain testosterone levels and treatment responses to identify these tumors.
December 2025 in “Fertility and Sterility” Both LNG-IUD and systemic progestins are effective for fertility-sparing treatment, but close monitoring is needed due to recurrence risk.
April 2025 in “The Obstetrician & Gynaecologist” Hirsutism is managed by assessing testosterone levels and using oral contraceptives, with ethical considerations on treatment access.
6 citations
,
June 2006 in “International Journal of Gynecological Pathology” A postmenopausal woman's hormone imbalance and symptoms improved after removing benign ovarian tumors.
18 citations
,
March 2010 in “Gynecologic and obstetric investigation” The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
January 2021 in “touchREVIEWS in Endocrinology” Surgery successfully treated a hidden ovarian tumor causing hair loss and excess hair growth in a postmenopausal woman.
9 citations
,
August 1952 in “The Journal of Clinical Endocrinology & Metabolism” A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
3 citations
,
October 1995 in “Southern Medical Journal” Finasteride may cause breast enlargement, low testosterone a risk factor.
7 citations
,
August 2019 in “Journal of Ovarian Research” Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
32 citations
,
January 2010 in “Journal of Korean Medical Science” A rare adrenal tumor in a 14-year-old girl caused male-like symptoms and was successfully removed.
January 2016 in “AACE Clinical Case Reports” Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.
2 citations
,
January 2014 in “International Journal of Endocrinology” Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.
December 2022 in “Journal of Medical Case Reports” A 20-year-old woman was found to have a rare ovarian tumor causing symptoms like acne and a low-pitched voice, which disappeared after the tumor was removed.
July 2023 in “Endocrinology, diabetes & metabolism case reports” Sertoliform endometrioid carcinoma of the ovary, though rare, has a good prognosis when treated early.
March 2023 in “Bagcılar medical bulletin” A young woman had a rare tumor causing high male hormone levels and symptoms like excessive hair and acne. After removing the tumor, her hormone levels returned to normal. Early diagnosis is important.
1 citations
,
May 2024 in “The Journal of Sexual Medicine” Clomiphene Citrate can quickly restore fertility in some men after long-term steroid abuse.
July 2024 in “Journal of Pediatric Endocrinology and Metabolism” Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.
October 2023 in “Journal of the Endocrine Society” The document concludes that doctors should thoroughly check postmenopausal women with sudden increased male traits for rare conditions like androgen-producing endometrial cancer.
December 2021 in “Aegean journal of obstetrics and gynecology” A woman's male-like physical changes were caused by two rare ovarian conditions.
March 2024 in “The journal of sexual medicine” The therapies improved ejaculation disorders and sexual function in middle-aged men.
21 citations
,
December 1977 in “Journal of pediatric surgery” Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
May 2021 in “Journal of the Endocrine Society” A woman developed male characteristics after using unregulated hormone therapy.
2170 citations
,
September 2017 in “The Journal of Clinical Endocrinology & Metabolism” A multidisciplinary approach is crucial for safe and effective hormone treatment in gender-dysphoric individuals, with specific guidelines for adolescents and adults.
1 citations
,
April 2022 in “Indian Journal of Plastic Surgery” Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.
9 citations
,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism”
November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.
11 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.
26 citations
,
July 2019 in “Fertility and Sterility” Reproductive gynecologists are the main referrers for male infertility evaluations in North America.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.