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Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Testosterone affects brain functions and contributes to sex differences, influencing conditions like autism.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

The pituitary gland functions normally even after losing most SOX2+ stem cells.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

AMT may cause hair loss and changing dWAT activity could help treat it.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Transgender individuals face insurance barriers to gender-affirming surgery, needing policy reforms for better access.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.