94 citations
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January 2000 in “The Journal of Clinical Endocrinology and Metabolism” Spironolactone most effective for hirsutism, but has side effects.
77 citations
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June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
77 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
75 citations
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February 2016 in “The Journal of Sexual Medicine” Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
73 citations
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February 2007 in “The American Journal of Medicine” PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.
71 citations
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November 2009 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.
66 citations
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September 2008 in “Dermatologic therapy” The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
65 citations
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May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
62 citations
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April 2004 in “Expert Opinion on Pharmacotherapy” Finasteride effectively treats male pattern baldness, improving hair growth and density.
50 citations
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January 2016 in “The Journal of Clinical Endocrinology and Metabolism” Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
49 citations
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July 2021 in “Nutrients” Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.
49 citations
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September 2012 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.
49 citations
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August 1996 in “The Journal of Clinical Endocrinology and Metabolism” The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
48 citations
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May 2012 in “Journal of Midwifery & Women's Health” Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.
42 citations
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January 2024 in “Frontiers in Endocrinology” Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
41 citations
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April 2010 in “Gender Medicine” The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
40 citations
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April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
39 citations
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April 2024 in “Frontiers in Endocrinology” New treatments aim to improve thin endometrium to help more couples with infertility.
39 citations
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October 2014 in “Schweizerische medizinische Wochenschrift” Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
34 citations
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February 2016 in “Fertility and Sterility” More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.
32 citations
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October 2003 Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
32 citations
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April 1999 in “Expert Opinion on Investigational Drugs” Finasteride effectively treats male hair loss, improving growth and density.
31 citations
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February 2021 in “Nutrients” Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.
30 citations
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April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
29 citations
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January 2007 in “Dermatologic Clinics” Photodynamic Therapy is an effective treatment for mild to severe acne.
28 citations
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August 2009 in “Nursing for Women's Health” Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
28 citations
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November 2007 in “Medical Clinics of North America” Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.
28 citations
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August 2003 in “Steroids” Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
27 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
27 citations
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November 1998 in “Journal of Endocrinological Investigation” Finasteride significantly reduces hair growth in women with idiopathic hirsutism.