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Neuroendocrinology of Human Scalp Hair Follicles: Growth Hormone-Releasing Hormone Stimulates Hair Growth and Controls a Fully Functional Intrafollicular Hypothalamic-Pituitary-Somatotropic Signaling Axis

research 562 Neuroendocrinology of human scalp hair follicles: Growth hormone-releasing hormone (GHRH) stimulates hair growth and controls a fully functional intrafollicular hypothalamic-pituitary-somatotropic (HPS) signaling axis

November 2022 in “Journal of Investigative Dermatology”

Growth hormone-releasing hormone (GHRH) boosts hair growth and human scalp hair follicles have their own growth hormone system.

research 269 The PPAR-γ modulator, N-acetyl-GED, protects from epithelial-mesenchymal-transition to human hair follicles: Potential relevance for scarring alopecia

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.

research Effect of gamma-ray exposure on the genome-editing efficiency of improved genome-editing via oviductal nucleic acids delivery (i-GONAD)

January 2025 in “EXPERIMENTAL ANIMALS”

Gamma-ray exposure improves genome editing efficiency in mice using the i-GONAD method.

research Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo

3 citations , January 2022 in “Burns & Trauma”

CTHRC1 helps sweat glands recover by rebuilding nearby blood vessels.

research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53

99 citations , August 2009 in “Nature Genetics”

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

research Identification of the Rat Rex Mutation as a 7-bp Deletion at Splicing Acceptor Site of the Krt71 Gene

45 citations , January 2010 in “Journal of Veterinary Medical Science”

A gene mutation causes curly hair and hair loss in rats.

research Analysis of skin graft survival using green fluorescent protein transgenic mice

19 citations , January 2007 in “Journal of medical investigation”

GFP transgenic mice help study cell origins in skin grafts.

research Pre-receptor regulation of the androgen receptor

56 citations , November 2007 in “Molecular and cellular endocrinology”

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

research Platelet-Rich Plasma In Androgenetic Alopecia:An Evidence-Based Clinical And Biological Review

January 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

PRP shows promise for improving hair growth in early to moderate hair loss but needs standardized methods for consistent results.

research The mechanism of activated platelet‐rich plasma supernatant promotion of hair growth by cultured dermal papilla cells

14 citations , March 2019 in “Journal of Cosmetic Dermatology”

Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.

The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

research The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals

17 citations , October 2003 in “Brazilian Journal of Medical and Biological Research”

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

research 5α-reductase activity in the prostate

237 citations , December 2001 in “Urology”

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

research An injectable bioactive dressing based on platelet-rich plasma and nanoclay: Sustained release of deferoxamine to accelerate chronic wound healing

62 citations , November 2022 in “Acta Pharmaceutica Sinica B”

The injectable hydrogel effectively speeds up chronic wound healing.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

research The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3

37 citations , August 2015 in “The Journal of Steroid Biochemistry and Molecular Biology”

The vitamin D receptor can regulate genes and affect hair and hormone levels without its usual activator.

research My Experiences in Using Autologous Human Hair Follicular Stem Cells (AMT) With Regenera Technology Combination With Platelet Rich Plasma (PRP) for Androgenetic Alopecia Treatments – in Both Male Pattern Hair Loss (MPHL)&Female Pattern Hair Loss (FPHL) in Asian Populations.

January 2020 in “Journal of Genetics and Gene Therapy”

The combination of hair follicle stem cells and PRP shows promise for treating hair loss in Asian men and women.

research Significance of the polyglutamine tract polymorphism in the androgen receptor

54 citations , November 2001 in “Urology”

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

research Overexpression of cotton Trihelix transcription factor GhGT-3b_A04 enhances resistance to Verticillium dahliae and affects plant growth in Arabidopsis thaliana

February 2023 in “Journal of Plant Physiology”

research The neurosteroid metabolite of progesterone, 3α‐OH‐dihydroprogesterone (3α‐OH‐DHP), is required for attenuated baroreflex mediated sympathoexcitation in pregnancy

1 citations , April 2013 in “The FASEB Journal”

3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.

research TRPV1 Function in Health and Disease

65 citations , December 2010 in “Current Pharmaceutical Biotechnology”

TRPV1 is involved in pain, various body functions, and diseases, but targeting it for treatment is challenging.

research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells

18 citations , February 2018 in “International Journal of Molecular Sciences”

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor

December 2016 in “Springer eBooks”

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.