355 citations
,
August 2013 in “Acta Biomaterialia” The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
123 citations
,
May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
81 citations
,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
73 citations
,
September 2016 in “Journal of Translational Medicine” Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
68 citations
,
November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
60 citations
,
May 2011 in “Endocrinology and Metabolism Clinics of North America” Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
55 citations
,
April 2018 in “Advanced Healthcare Materials” Hydrogels could lead to better treatments for wound healing without scars.
53 citations
,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
48 citations
,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
45 citations
,
May 2019 in “Scientific Reports” Low color temperature light (1900 K) benefits health by promoting melatonin, protecting eyes, and aiding healing.
45 citations
,
February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
44 citations
,
October 2017 in “Scientific Reports” Far-infrared radiation improves stem cell growth and movement, helping heart therapy.
44 citations
,
July 2015 in “JAMA Facial Plastic Surgery” Fractional laser resurfacing is effective and safe for skin treatment, with benefits like less downtime and a low risk of adverse events.
41 citations
,
October 2017 in “International Journal of Women's Dermatology” Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.
40 citations
,
June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
39 citations
,
January 2012 in “Acta dermato-venereologica” Early detection and stopping the drug are key to managing DRESS, and careful monitoring is important due to possible severe reactions.
35 citations
,
June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
33 citations
,
April 2011 in “Journal of Veterinary Internal Medicine” Long-term fluticasone treatment does not harm the immune system in horses with heaves.
33 citations
,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
31 citations
,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
30 citations
,
August 2016 in “Advances in radiation oncology” Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
30 citations
,
March 2015 in “PLoS ONE” Thyroxine can adjust the body's peripheral clock, potentially helping treat clock-related diseases.
28 citations
,
January 2015 in “Skin appendage disorders” Children with trichotillomania often pull hair from their scalp, and parents may not notice; stress can trigger it, and asking detailed questions helps in diagnosis and treatment.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).
24 citations
,
May 2019 in “PLOS ONE” The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
24 citations
,
April 2017 in “Journal of Investigative Dermatology” Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
22 citations
,
May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
20 citations
,
November 2019 in “Current Opinion in Systems Biology” The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
19 citations
,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.