April 2026 in “Cosmetics” The shampoo effectively covers gray hair gradually and maintains color after multiple washes.
April 2026 in “International Journal of Dermatology”
May 2023 in “Health science reports” Coloring shampoos for gray hair may cause gene mutation, reproductive issues, and skin damage, needing stricter regulation and expert consultation.
November 2022 in “Skin Appendage Disorders” PT-20 did not significantly improve gray hair repigmentation.
May 2025 in “International Journal Of Science Technology & Management” The pomade business is viable with a 1.24 R/C Ratio.
September 1941 in “The Science News-Letter” 56 citations
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July 2001 in “International Journal of Clinical Pharmacology and Therapeutics” People obsessed with looking young may need therapy to address deeper issues.
February 1945 in “New England Journal of Medicine” 2 citations
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January 2012 in “Zhongguo nongye Kexue” EGF helps secondary hair follicles grow in young gray goats.
March 1942 in “The Science News-Letter”
1 citations
,
January 2021 in “Pakistan journal of zoology” Red fox, golden jackal, and gray wolf hairs have similar features but differ in length, thickness, and inner structure.
4 citations
,
September 1944 in “The American Journal of the Medical Sciences”
260 citations
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June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
210 citations
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May 2006 in “The FASEB journal” Oxidative stress causes hair to gray by damaging and killing pigment cells.
63 citations
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February 2017 in “ACS biomaterials science & engineering” Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
56 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
46 citations
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April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.
35 citations
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January 2013 in “International Journal of Trichology” Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.
30 citations
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April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
27 citations
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October 2020 in “Experimental Dermatology” Having a lot of gray hair and hair loss are linked to more severe COVID-19.
16 citations
,
January 2018 in “International journal of trichology” Genetics and nutritional deficiencies are key factors in premature graying of hair.
11 citations
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May 2012 in “Genesis” Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
10 citations
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May 2021 in “Clinical, cosmetic and investigational dermatology” UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.
9 citations
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November 2015 in “JAMA dermatology” A 91-year-old woman's hair turned black in one spot, with skin changes underneath.
7 citations
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January 2018 in “Asian journal of pharmaceutical research” The polyherbal hair oil effectively treats various hair problems.
6 citations
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March 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Most people in Turkey start getting gray hair around 33 years old, with factors like age, education, hair loss, skin type, family history, and anxiety playing a role.
5 citations
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January 2023 in “International Journal of Molecular Sciences” Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
2 citations
,
November 2022 in “Journal of Biochemistry and Molecular Biology” Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
2 citations
,
June 2020 in “Journal of Drug Delivery and Therapeutics” The document concludes that understanding hair problems can lead to cost-effective solutions and proper treatment choices.
1 citations
,
February 2021 in “International Journal of Research in Dermatology” Premature graying of hair significantly harms psychological and social wellbeing.