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research A novel MBTPS2i> variant associated with BRESHECK syndrome impairs sterol‐regulated transcription and the endoplasmic reticulum stress response

5 citations , October 2021 in “American Journal of Medical Genetics Part A”

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

research 1342 Spatial transcriptome profiling reveals TGFβ-2 in hair follicle progenitor cells is a potential driver of androgenetic alopecia
April 2023 in “Journal of Investigative Dermatology”

TGFβ-2 may cause hair loss in androgenetic alopecia.

research Purification and characterization of rat liver minoxidil sulphotransferase
29 citations , September 1990 in “Biochemical Journal”

Enzyme purified and characterized for minoxidil sulphation in rat liver.

research Selective isomerization of α-pinene oxide to campholenic aldehyde by ionic liquid-supported indenyl-molybdenum(II)-bipyridine complexes
6 citations , May 2022 in “Journal of Organometallic Chemistry”

The process efficiently converts α-pinene oxide to campholenic aldehyde using a special catalyst, achieving high yields quickly.

research Novel ALK5 inhibitor TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles
14 citations , January 2017 in “Pharmacological Reports”

TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.

research Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71 rco12 and Krt71 rco13
51 citations , December 2006 in “Mammalian Genome”

research Enhancing 1α-Hydroxylase Activity with the 25-Hydroxyvitamin D-1α-Hydroxylase Gene in Cultured Human Keratinocytes and Mouse Skin
18 citations , June 2001 in “Journal of Investigative Dermatology”

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

research Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament
27 citations , November 2007 in “Genomics”

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

research 455 Beyond Immunity: TEC and JAK3 Kinase Activation in Melanocytes Drives Inflammation in Vitiligo
November 2025 in “Journal of Investigative Dermatology”

TEC kinases may help cause inflammation in vitiligo and could be targeted for treatment.

research KRT72 wt Allele
February 2020 in “Definitions”

KRT72 gene helps form hair.

research The role of Atg5i> gene in tumorigenesis under autophagy deficiency conditions
4 citations , June 2024 in “The Kaohsiung Journal of Medical Sciences”

Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.

research A carrier-free injectable hydrogel self-assembled using natural thymol and glycyrrhizin for MRSA-infected wound healing in rats
April 2024 in “Chemical engineering journal”

The new hydrogel made from thymol and glycyrrhizin helps heal MRSA-infected wounds in rats effectively.

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21
98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
1 citations , January 2024

CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.

research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
January 2024

CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.

research The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth
17 citations , May 2011 in “Gene Therapy”

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

research Isoallopregnanolone reduces tic‐like behaviours in the D1 CT ‐7 mouse model of Tourette syndrome
15 citations , June 2019 in “Journal of Neuroendocrinology”

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

research The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles
51 citations , January 2004 in “European Journal of Cell Biology”

Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.

research 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism.
179 citations , May 1982 in “The Journal of clinical investigation/The journal of clinical investigation”

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

research Transgenic mice display hair loss and regrowth overexpressing mutant <i>Hr</i> gene
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu”

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

research Characterization of Recombinant Human Liver Thermolabile Phenol Sulfotransferase with Minoxidil as the Substrate
16 citations , May 1995 in “Biochemical and Biophysical Research Communications”

Both enzyme forms can sulfate minoxidil.

research A Girl with a Novel Splice Site Mutation in <i>VDR</i> Supports the Role of a Ligand-Independent VDR Function on Hair Cycling
21 citations , January 2006 in “Hormone Research in Paediatrics”

A mutation in the VDR gene affects hair cycling without needing ligand binding.

research Tyrosinase inhibition due to interaction of homocyst(e)ine with copper: the mechanism for reversible hypopigmentation in homocystinuria due to cystathionine beta-synthase deficiency.
74 citations , July 1995 in “PubMed”

Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.

research A case report of a novel homozygote mutation causing severe Leydig cell hypoplasia: insights in the coexistence of nonsense mutation and polymorphism in the same LHCGR gene locus
November 2012 in “Experimental and Clinical Endocrinology & Diabetes”

A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.

research Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity
372 citations , December 2004 in “Nature Genetics”

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles
19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

research Treatment of Cystathionine β-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector
14 citations , May 2019 in “Human gene therapy”

MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.

research Identification of Pygopus 2 as a component of the ribosomal RNA transcription complex in cancer
January 2008 in “Memorial University Research Repository (Memorial University)”

Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.

research Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo “hairless” rat
28 citations , October 2004 in “Differentiation”

A gene deletion causes the "hairless" trait in Iffa Credo rats.

research 376 Tsc2 disruption in mesenchymal progenitors regulates hair follicles and TGF beta signaling
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

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