Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.
January 2015 in “Zhongguo haiyang yaowu” Collagen from puffer skin may help whiten skin and slow aging without harm.
January 1985 in “Clinical research” Topical alpha-terthienyl with UVA may safely treat psoriasis without cancer risk.
1 citations
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January 2020 in “VTechWorks (Virginia Tech)” αCT1 improves scar appearance by changing early collagen structure.
118 citations
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June 1993 in “Journal of Biological Chemistry” Human and mouse TGase3 enzymes are similar but differ near the activation site, crucial for their function in skin and hair development.
116 citations
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April 1986 in “The journal of cell biology/The Journal of cell biology” Trichohyalin is a protein in hair follicles that helps form hair filaments.
36 citations
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March 2014 in “Biomaterials” A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
28 citations
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January 2004 in “British Journal of Pharmacology” Minoxidil protects heart and improves recovery.
10 citations
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January 1985 in “PubMed” Trace elements like calcium, iron, and zinc are unevenly distributed in hair, while sulfur is even, and increased phosphorus and potassium levels are linked to skin reactions.
3 citations
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April 2015 in “Current problems in dermatology” A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
June 2023 in “Journal of Pharmaceutical and Health Research” Caffeine hair tonic with 0.001% concentration was more effective in promoting hair growth on guinea pigs.
12 citations
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February 2017 in “International journal of developmental neuroscience” Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.
March 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Health issues in retired breeder guinea pigs don't affect experiment success.
39 citations
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November 2016 in “Pharmaceutics” The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
211 citations
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June 2012 The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
53 citations
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November 1997 in “Journal of Forensic Sciences” Darker hair in guinea pigs holds more codeine than lighter hair.
August 2025 in “Annals of Medicine” Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
353 citations
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November 2014 in “Molecular immunology” Porcine skin is very similar to human skin, making it a useful model for research.
2 citations
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March 2015 in “Toxicology and Environmental Health Sciences” Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.
15 citations
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June 1964 in “Experimental Biology and Medicine” Methotrexate can temporarily suppress certain immune responses without killing immune cells, potentially helping treat autoimmune diseases.
24 citations
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December 1957 in “Experimental Cell Research” The glassy layer of hair follicles has different fibril sizes and arrangements in guinea pigs and young mice.
2 citations
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January 2016 in “Skin pharmacology and physiology” Caragana korshinskii seed oil effectively treats fungal skin infections.
30 citations
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May 1999 in “Food and chemical toxicology” Procyanidin B-2 is safe to use on skin as a hair growth product.
12 citations
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November 1945 in “Archives of dermatology” Transplanted skin on hooded rats often grows white hair instead of black.
7 citations
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January 2022 in “Animal Reproduction” Using rodents for research shows that health problems in the womb can cause diseases later in life.
3 citations
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April 1990 in “Archives of dermatology” The book reveals diverse patterns of hair growth in different species and advancements in hair and alopecia research.
1 citations
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April 1976 in “Archives of Dermatology” Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.
January 1995 in “Equilibrium Research” Birds can regenerate inner ear hair cells from supporting cells, and mammals show potential for similar regeneration.
28 citations
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January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.