research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
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research Evaluation of the Efficacy of Antihistamines in the combined therapy for Alopecia Areata
Combining antihistamines with topical treatment improves hair regrowth in alopecia areata.
research Hormonal changes and hair growth during treatment of hirsutism with cimetidine.
Cimetidine does not significantly reduce hair growth in hirsutism.
research 270 A novel small compound HPH-15 antagonizes TGF-β/Smad signaling and ameliorates experimental skin fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research Docking-based workflow and ADME prediction of some compounds in Curcuma longa and Andrographis paniculata as polymerase PA-PB1 inhibitors of influenza A/H5N1 virus
Compounds from turmeric and bitter show strong potential as antiviral agents against the influenza A virus.
research Adrenolytic and Vasodilator Therapy
New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
research Effect of a nutritional supplement on hair loss in women
The nutritional supplement improved hair density and reduced hair loss in women with female pattern hair loss.
research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research The effects of benzodiazepines on hormones in women with idiopathic hirsutism
Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.
research STUDIED ON TOXICITY OF HYDROCORTISONE 17-BUTYRATE 21-PROPIONATE : 6. Subacute Toxicity in Dogs by Percutaneous Adminisration
Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.
research Design, synthesis and anti-tumor evaluation of novel thiohydantoin congeners as androgen receptor antagonists with in vivo study.
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research A Natural Product Molecule of Artocarpus Heterophyllus Reverses Inflammation Due to the Effect of Acute Exposure of Prostate Tissue to Testosterone Enanthate in Wistar Rats
Artocarpus heterophyllus seed extract may help treat prostate inflammation without side effects.
research Inhibition of class I HDACs preserves hair follicle inductivity in postnatal dermal cells
Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
research Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model
Human placenta extract reduces inflammation and symptoms in atopic dermatitis.
research BIOLOGICAL ACTIVITY OF ANTIANDROGENS
Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
research Recent Progress in Health Benefits of Hederagenin and Its Glycosides
Hederagenin shows promise for cancer and inflammation treatment but needs modifications to improve effectiveness.
research p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen)
Blocking a specific receptor slows down hair loss in mice.
research Treatment Options for Hirsutism: A Systematic Review and Network Meta-Analysis
Oral contraceptives and antiandrogens are effective for treating hirsutism, with antiandrogens being the most effective.
research The anticonvulsant effects of progesterone and its metabolites
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
research The Treatment of Resistant Hypertension
New treatments improved blood pressure control in patients with resistant hypertension.
research Reduction of Diameter of Hair Shaft among Women with Hirsutism
Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
research HNG, A Humanin Analogue, Promotes Hair Growth by Inhibiting Anagen-to-Catagen Transition
HNG helps hair grow by keeping hair in the growth phase longer.
research Pre-receptor regulation of the androgen receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options
Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.
research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway
Applying a special compound can promote hair growth without harmful side effects.
research PSAT097 Patient Preference Research: Preferred Adjunctive Medication Attributes of Adult Patients with Classic Congenital Adrenal Hyperplasia
Adults with classic congenital adrenal hyperplasia value medication that prevents weight gain from glucocorticoids the most.
research A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism
Spironolactone plus finasteride reduces hirsutism more effectively.
![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
research New Therapeutic Approach to the Hirsute Patient
Spironolactone can reduce hair growth in women with hirsutism.
research Current Aspects of Antiandrogen Therapy in Women
Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.