A rigid compound with a common structural motif was successfully synthesized.
22 citations
,
August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
5 citations
,
January 2024 in “Crystals” The salts have diverse molecular packing with significant hydrogen interactions.
December 2024 in “Problems of Biological Medical and Pharmaceutical Chemistry” Students from the Middle East and Moscow have different hair element levels due to their environments.
27 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.
32 citations
,
January 2020 in “Journal of Molecular Histology” K31 can identify clear secretory cells in human sweat glands.
December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The KDM1 gene helps Venus flytraps close by managing potassium ions.
47 citations
,
September 2011 in “Acta biomaterialia” Protein composition greatly affects the function of keratin biomaterials.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
51 citations
,
September 2012 in “Biomacromolecules” Disulfide bonds make keratin in hair stronger and tougher.
15 citations
,
May 2009 in “Chemical Physics Letters” A new method accurately measures molecular movement without complex modeling.
21 citations
,
January 1995 in “Molecular Biology Reports” Scientists discovered two versions of a new human hair keratin gene.
2 citations
,
February 2021 in “FEBS open bio” Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
1 citations
,
June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” Chemical modifications can alter hair's stability and flexibility, with hydrophobic interactions helping maintain structure in humid conditions.
6 citations
,
March 1996 in “Journal of Investigative Dermatology” 46 citations
,
December 1998 in “Journal of Biological Chemistry” Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
13 citations
,
May 2016 in “International journal of biological macromolecules” Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
133 citations
,
June 1993 in “Molecular and Cellular Biology” The human K5 promoter controls specific gene expression in skin cells, with key regulatory elements near the TATA box.
7 citations
,
February 1998 in “Polymer journal” Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
477 citations
,
March 2004 in “Proceedings of the National Academy of Sciences” The DMI3 gene is essential for nodule development and symbiosis in certain plants.
5 citations
,
February 2010 in “Drug development and industrial pharmacy” Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.
July 1993 in “Journal of Radioanalytical and Nuclear Chemistry” Mouse hair element patterns vary, making it unreliable for tracking time.
2 citations
,
September 2020 in “Biomedical materials” Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
August 2016 in “Journal of Investigative Dermatology” EZH2 is essential for hair growth and skin cell development.
January 2002 in “Proceedings of The Japanese Society of Animal Models for Human Diseases” Keratin2-6g is crucial for hair follicle development, with mutations causing cell degeneration and vacuolation.
18 citations
,
November 2005 in “Archives of Dermatological Research” 252 citations
,
January 1991 in “Electron Microscopy Reviews” April 2016 in “한국고분자학회 학술대회 연구논문 초록집” 75 citations
,
October 1999 in “Differentiation” Mouse keratin 6 isoforms have different expression patterns in various tissues.