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research Uterus Hyperplasia and Increased Carcinogen-Induced Tumorigenesis in Mice Carrying a Targeted Mutation of the Chk2 Phosphorylation Site in Brca1

48 citations , October 2004 in “Molecular and Cellular Biology”

Mice with a specific BRCA1 mutation have a higher risk of tumors, especially in the uterus and ovaries.

research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect

June 2025 in “Proceedings of the National Academy of Sciences”

A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.

research Magnesium availability regulates the development of root hairs in Arabidopsis thaliana (L.) Heynh

82 citations , April 2014 in “Plant Cell & Environment”

Magnesium levels control root hair growth in plants.

research Transcriptome profiling of whisker follicles in methamphetamine self-administered rats

6 citations , July 2018 in “Scientific Reports”

Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.

research 671 The adenosine-generating ecto-enzyme, CD73, functions as an intrafollicular regulator of human hair growth

April 2016 in “Journal of Investigative Dermatology”

CD73 may regulate hair growth and could be targeted for hair growth treatments.

research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development

14 citations , May 2016 in “International Journal of Molecular Sciences”

PP2Acα is essential for proper hair and skin development.

research Marie Unna Hereditary Hypotrichosis Gene Maps to Human Chromosome 8p21 Near Hairless

29 citations , March 2000 in “Journal of Investigative Dermatology”

The gene for Marie Unna hereditary hypotrichosis is located on chromosome 8p21.

research Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet

January 2024 in “Journal of Hard Tissue Biology”

A high-fat diet may weaken tongue structure by reducing certain protein genes.

research A Homozygous Frameshift Mutation in theHOXC13Gene Underlies Pure Hair and Nail Ectodermal Dysplasia in a Syrian Family

30 citations , January 2013 in “Human Mutation”

A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.

research Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood

33 citations , June 2007 in “Gene Expression Patterns”

CTIP2 may help in skin development and maintenance.

research The citrullinating enzyme PADI4 governs progenitor cell proliferation and translation in developing hair follicles

September 2025 in “Science Advances”

PADI4 enzyme slows down cell growth in developing hair follicles.

research Genome-wide detection of RNA editing events during the hair follicles cycle of Tianzhu white yak

October 2022 in “BMC genomics”

RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.

research Localization and Regulation of Expression of the FAR-17A Gene in the Hamster Flank Organs

16 citations , July 1996 in “Journal of Investigative Dermatology”

research The TRF1 telomere protein is essential for the generation and maintenance of iPS cells and marks both pluripotent and adult stem cells

January 2013 in “edoc (University of Basel)”

TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.

research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

3 citations , December 2013 in “Journal of Cell Science”

Keratin 79 cells help form and regenerate hair canals.

research Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate

1 citations , April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Polyamines are important in deciding hair follicle stem cell behavior, affecting hair growth and loss.

research Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle

30 citations , October 1999 in “Differentiation”

Mutant MK6a transgenes in mice cause blistering, hair loss, and potential human alopecia.

research 0882 Patterning and regional specification of hairy skin

July 2025 in “Journal of Investigative Dermatology”

Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.

research The human keratins: biology and pathology

1398 citations , May 2008 in “Histochemistry and Cell Biology”

Keratins are crucial for cell stability, wound healing, and cancer diagnosis.

research Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice

October 2014 in “Cancer research”

Blocking mTORC1 reduces skin tumor growth in mice.

research Scraggly, a new hair loss mutation on mouse Chromosome 19

14 citations , September 1999 in “Mammalian genome”

The scraggly mutation causes hair loss and skin defects in mice.

research Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis

63 citations , November 2009 in “British journal of dermatology/British journal of dermatology, Supplement”

Sub3 is essential for fungus adherence but not for skin invasion.

Solid State NMR of Isotope Labeled Murine Fur: A Powerful Tool to Study Atomic Level Keratin Structure and Treatment Effects

research Solid state NMR of isotope labelled murine fur: a powerful tool to study atomic level keratin structure and treatment effects

10 citations , October 2016 in “Journal of Biomolecular NMR”

Solid-state NMR can effectively study keratin structure and treatment effects in fur.

research miR‐203a‐3p promotes loureirin A‐induced hair follicle stem cells differentiation by targeting Smad1

12 citations , June 2020 in “The anatomical record”

miR-203a-3p helps hair follicle stem cells become specialized by targeting Smad1.

research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene

January 2024 in “Animals”

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

research Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine

24 citations , October 2019 in “Genes”

A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.

Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link Between the Embryonic Subperiderm and Feather Barbs and Barbules

research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link between the Embryonic Subperiderm and Feather Barbs and Barbules

22 citations , December 2016 in “PloS one”

A specific protein in chicken embryos links early skin layers to feather development.

research 494 Congenital generalized hypertrichosis with a copy number variation on chromosome 17q24

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.

research The Catalog of Human Hair Keratins

272 citations , September 2001 in “Journal of Biological Chemistry”

Human hair keratins were cataloged, showing their roles in hair differentiation stages.

research Le gènehairlessde la souris

4 citations , May 2006 in “médecine/sciences”

The hairless gene is crucial for hair health, and its mutations cause hair loss.

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