54 citations
,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
48 citations
,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.
Hair restoration surgery has improved to transplant hair in natural groupings, but it's labor-intensive and can't fully restore normal hair density.
16 citations
,
November 2020 in “International journal of pharmaceutics” Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
1 citations
,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
40 citations
,
April 2006 in “Journal of the European Academy of Dermatology and Venereology” The Trichoscan system was found to be inaccurate for measuring hair growth, needing better software to be useful.
55 citations
,
October 2003 in “Dermatologic Clinics” Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.
18 citations
,
May 2016 in “Annals of Medicine” The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.
18 citations
,
November 2010 in “Journal of morphology” Antler velvet hair and body hair of red deer have different structures that help with protection and insulation.
16 citations
,
October 2015 in “Photochemistry and photobiology” Reducing copper (II) ion levels in hair can decrease hair damage.
15 citations
,
July 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
14 citations
,
November 2020 in “International Journal of Biological Macromolecules” Mushroom-based scaffolds help heal skin wounds and regrow hair.
5 citations
,
October 2020 in “Experimental dermatology” A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
August 2018 in “Journal of Investigative Dermatology” Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.
111 citations
,
March 1951 in “Annals of the New York Academy of Sciences” Understanding the mouse hair cycle is crucial for cancer research.
3 citations
,
November 1999 in “Journal of Cutaneous Medicine and Surgery” Examining scalp biopsies in different ways helps better diagnose hair loss types.
22 citations
,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
3 citations
,
January 2018 in “International Journal of Cosmetic Science” Hair stiffness increased by 13.2% after caffeine treatment, validating the Stiffness-Angle Law as an effective measurement method.
1 citations
,
July 2019 in “British Journal of Dermatology” Minoxidil was more effective than laser therapy for hair loss, and the report also highlighted the need for more research on PRP for a different hair loss condition, the impact of social media on alopecia views, and a warning on turmeric causing nail discoloration.
January 2022 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.
1 citations
,
May 2002 in “British Journal of Dermatology” Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.
May 2002 in “British Journal of Dermatology” Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.
1 citations
,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
January 2019 in “Durham e-Theses (Durham University)” Advanced microscopy shows hair damage and keratin proteins' roles, aiding future cosmetic treatments.
June 2026 in “Research Square” The study highlights the crucial role of THBS4 in hair regeneration by modulating the mechanical properties of the dermal niche, which reduces matrix stiffness and enhances interactions between the epidermis and dermis. This process activates hair follicle stem cells (HFSCs) and accelerates the transition from the telogen to anagen phase, promoting hair growth. THBS4 upregulation in dermal fibroblasts activates signaling pathways involving ITGB1, EGR1, and HMGCR, facilitating HFSC proliferation. Experiments with mice and organoids showed that THBS4 treatment significantly enhances hair regeneration, suggesting its potential as a therapeutic target for hair loss treatments. Further research is needed to explore the detailed mechanisms of THBS4 in extracellular matrix assembly and metabolic reprogramming.
51 citations
,
January 2004 in “Skin Pharmacology and Physiology” The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
38 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
396 citations
,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.