Hedgehog signaling can create new hair follicles but may also cause tumors.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
90 citations
,
December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
71 citations
,
February 2000 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Estradiol stops hair growth in mice, but an antagonist can reverse this effect.
50 citations
,
October 2011 in “Archives of Biochemistry and Biophysics” Vitamin D receptor is essential for healthy hair growth.
49 citations
,
April 2006 in “Journal of Investigative Dermatology” TRPV1 helps regulate hair growth cycles.
27 citations
,
April 2020 in “PLoS ONE” Hair follicle stem cells in cashmere goats show different gene activity during hair growth phases.
25 citations
,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
22 citations
,
February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
19 citations
,
April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
17 citations
,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Stat3 is essential for hair growth and wound healing.
11 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
8 citations
,
July 2020 in “BMC genomics” The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.
7 citations
,
September 2003 in “Journal of Investigative Dermatology” PAR-1 may play a role in hair growth regulation in human hair follicles.
5 citations
,
January 2016 in “Genetics and Molecular Research” Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.
2 citations
,
December 2024 in “BMC Genomics” Key genes and pathways control sheep hair growth phases.
1 citations
,
September 2018 in “Australasian Journal of Dermatology” A boy with GAPO syndrome had hair loss similar to male pattern baldness without hormone issues, possibly due to skin or blood vessel problems.
May 2026 in “Frontiers in Pharmacology” Dendrobium officinale polysaccharide helps hair regrowth in hair loss mice by affecting local steroid metabolism and hair follicle responses.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MPZL3 is important for controlling the hair growth cycle in mice and humans.
The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.
30 citations
,
October 2014 in “Experimental Dermatology” Leptin from skin fat can slow hair growth during certain phases.
86 citations
,
February 2012 in “Journal of Clinical Investigation” Stem cells in hair follicles are diverse and change throughout the hair cycle.
24 citations
,
May 2009 in “The FASEB Journal” Akt2 and SGK3 are both important for normal hair growth and development.
7 citations
,
March 2012 in “Journal of Investigative Dermatology” Some thymic peptides can increase human hair growth, while others may inhibit it.
2 citations
,
April 2019 in “Experimental Dermatology” Hair follicles respond differently to pulling forces in various regions.
1 citations
,
July 2025 in “JCI Insight” Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” A pomade with peppermint oil and minoxidil can effectively promote hair growth, with the best formulation having a balanced texture and stability.
February 2025 in “Journal of Fundamental and Applied Pharmaceutical Science” The hair tonic with mangosteen peel extract is suitable and meets necessary requirements.
September 2023 in “Jurnal MIPA (edisi elektronik)” Lime extract can be used to make a stable hair tonic with beneficial compounds.