16 citations
,
November 2013 in “European Journal of Dermatology” Hair gets thinner and grayer with age, and density decreases more in men on top and in women on top and back.
28 citations
,
December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
24 citations
,
March 1995 in “British Journal of Dermatology” Etretinate therapy can cause hair loss by disrupting the hair growth cycle.
April 2019 in “Journal of emerging technologies and innovative research” Early treatment of Female Pattern Hair Loss is important to stop it from getting worse, and various treatments can help, especially in mild to moderate cases.
46 citations
,
April 2009 in “Journal of Dermatological Case Reports” Researchers established normal hair and scalp characteristics for healthy women using trichoscopy.
56 citations
,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
6 citations
,
January 2020 in “International journal of biological sciences” Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
2 citations
,
April 2017 in “Molecular Medicine Reports” Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.
109 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
97 citations
,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
92 citations
,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
33 citations
,
September 2019 in “Dermatologic Surgery” Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.
11 citations
,
April 2016 in “The American Journal of Dermatopathology” Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.
7 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
5 citations
,
January 2021 in “Skin appendage disorders” Smoking is linked to more hair loss and premature graying compared to nonsmokers.
5 citations
,
July 2019 in “Atlas of the Oral and Maxillofacial Surgery Clinics” Tissue expansion for head and neck reconstruction has good blood supply and doesn't need capsule removal, but expect temporary hair loss with normal growth resuming after 6-8 months.
4 citations
,
October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
98 citations
,
November 2002 in “Contact Dermatitis” Many people had severe allergic reactions to a common hair dye ingredient, causing them to seek medical care and miss work.
27 citations
,
March 2013 in “Social Semiotics” Commercial hair loss websites promote Propecia by making men feel insecure about baldness and suggesting it's a medical issue needing treatment.
Polarized microscopy helps identify hair irregularities in genetic disorders.
51 citations
,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
17 citations
,
May 2018 in “Journal of Cosmetic Dermatology” Most women in the study lost hair due to chronic shedding, with stress and nutrient deficiencies being common factors.
Female pattern hair loss, common in women, can be treated with various methods like minoxidil, anti-androgen treatments, and light therapy, but early intervention and realistic expectations are crucial.
314 citations
,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
194 citations
,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
99 citations
,
June 2005 in “Journal of Cosmetic Dermatology” Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
46 citations
,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
25 citations
,
May 2003 in “Expert Opinion on Therapeutic Patents” Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
21 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.