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ATP-Competitive mTOR Kinase Inhibitors Delay Plant Growth by Triggering Early Differentiation of Meristematic Cells Without Developmental Patterning Change

research ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

161 citations , August 2013 in “Journal of experimental botany”

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum Copticum Seeds

research Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum copticum (L.) Link Seeds

August 2018

Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.

research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

Researchers found WNT10A to be a key gene in developing goat hair follicles.

research The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors

18 citations , November 2005 in “Archives of Dermatological Research”

research Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis

13 citations , April 2022 in “Frontiers in oncology”

Melanoma development can be linked to the breakdown of skin's melanin-producing units.

research Importance of Citrullination on Hair Protein Molecular Assembly During Trichocytic Differentiation

5 citations , September 2013

Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia

research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells (SH-MSCs) on IL-10 and TNF- α Gene Expression (In Vivo Experimental Study in Male Rats of Wistar Strains Model of Fluconazole-Induced Alopecia)

December 2023 in “International journal of multidisciplinary research and analysis”

SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

Expression of Anti-Aging Type-XVII Collagen (COL17A1/BP180) in Hair Follicle-Associated Pluripotent (HAP) Stem Cells During Differentiation

research Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation

11 citations , June 2019 in “Tissue & Cell”

Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.

Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus Terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis

research Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis

5 citations , May 2022 in “Biomedicines”

Botryococcus terribilis and its compounds may promote hair growth and improve hair health.

research Arabidopsis ZINC FINGER PROTEIN1 Acts Downstream of GL2 to Repress Root Hair Initiation and Elongation by Directly Suppressing bHLH Genes

101 citations , November 2019 in “The Plant Cell”

AtZP1 protein stops root hair growth in plants by blocking certain genes.

Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion

research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion

72 citations , November 2012 in “PloS one”

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

research Hair growth-promoting effects of Stellera chamaejasme L. extract on C57BL/6 mice via induction of anagen phase genes

May 2025 in “Journal of Traditional Chinese Medical Sciences”

Stellera chamaejasme L. extract promotes hair growth by activating hair growth genes.

MRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia

research mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia

December 2023 in “International Journal of Molecular Sciences”

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

research Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair

119 citations , August 2008 in “BMC Evolutionary Biology”

KRTAP genes evolved early in mammals, leading to diverse hair traits.

research Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families

40 citations , December 2010 in “Human Genetics”

research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma

7 citations , February 2009 in “Cell and tissue biology”

research Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases

47 citations , July 2023 in “Nature Genetics”

research Evaluation of the Effect of NT-3 and Biodegradable Poly-l-lactic Acid Nanofiber Scaffolds on Differentiation of Rat Hair Follicle Stem Cells into Neural Cells In Vitro

19 citations , August 2013 in “Journal of Molecular Neuroscience”

research Abstract C4: Sp2: A regulator of stem cell differentiation and tumorigenesis

December 2009 in “Cancer Research”

Over-expression of Sp2 can lead to cancer by preventing proper stem cell differentiation.

research Sequences and differential expression of three novel human type-II hair keratins

61 citations , February 1997 in “Differentiation”

Hair differentiation starts earlier than thought, involving multiple type-II keratins.

research MicroRNA-148a Controls Epidermal and Hair Follicle Stem/Progenitor Cells by Modulating the Activities of ROCK1 and ELF5

1 citations , September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.

research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge

387 citations , November 2003 in “Journal of Investigative Dermatology”

The K15 promoter effectively targets stem cells in the hair follicle bulge.

research Exploiting the Keratin 17 Gene Promoter To Visualize Live Cells in Epithelial Appendages of Mice

58 citations , July 2005 in “Molecular and Cellular Biology”

A specific gene segment can make mouse skin cells glow, helping study hair growth and gene effects.

research Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth

11 citations , February 2023 in “British Journal of Pharmacology”

Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.

research Ribonucleic Acids Coding for the Keratin Complex of Hair

5 citations , January 1981

Keratin proteins in hair are complex and come from multiple gene families.

research 1362 Dermal papilla cell-derived extracellular vesicles as the future tools for hair regeneration

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Dermal papilla cell-derived exosomes can help stem cells grow hair.

research Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation.

104 citations , July 1994 in “The Journal of Cell Biology”

Basonuclin helps keratinocytes multiply and prevents them from fully maturing.

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