236 citations
,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
155 citations
,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
71 citations
,
June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
53 citations
,
May 2010 in “Journal of Cellular Physiology” Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
26 citations
,
October 2016 in “Biomolecules & Therapeutics” 3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
15 citations
,
September 2008 in “Archives of Dermatological Research” Roxithromycin, an antibiotic, can increase hair growth and might be used as a treatment for hair loss.
9 citations
,
January 2015 in “Laboratory Animal Research” Laminaria japonica and Cistanche tubulosa extracts combined may effectively promote hair growth.
7 citations
,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
4 citations
,
January 2021 in “Dermatologic Therapy” AI is effective in diagnosing and treating hair disorders, including detecting hair loss and scalp conditions with high accuracy, but it should supplement, not replace, doctor-patient interactions.
3 citations
,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
12 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” Hair transplantation is the only permanent solution for female pattern hair loss and can greatly improve quality of life with careful planning.
4 citations
,
August 2013 in “Expert Review of Dermatology” Updated treatments for female hair loss include minoxidil, antiandrogens, hair transplants, and light therapy.
January 2007 in “Journal of the American Academy of Dermatology” A 73-year-old man's grey-white hair turned dark brown after eczema treatment.
146 citations
,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
134 citations
,
September 2008 in “Lasers in surgery and medicine” Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
39 citations
,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
37 citations
,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
30 citations
,
July 2017 in “Stem cells and cloning” SVF-enhanced adipose transplantation shows potential as a hair loss treatment.
29 citations
,
March 2008 in “Postcolonial Studies” The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.
26 citations
,
September 1969 in “The American journal of medicine” Cronkhite-Canada Syndrome often leads to death within 6-18 months.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
22 citations
,
February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
21 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.
13 citations
,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
13 citations
,
July 2011 in “Photomedicine and laser surgery” Coloring white hair before IPL treatment effectively helps remove it.
12 citations
,
December 1987 in “Cancer Chemotherapy and Pharmacology” Vitamin E in the diet might help protect against hair loss caused by the chemotherapy drug doxorubicin in rabbits.
10 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
9 citations
,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
3 citations
,
July 1997 in “Current problems in dermatology” Hair restoration surgery has evolved over time, with a focus on natural-looking results and managing patient expectations, while also considering potential complications and the lifelong progression of male pattern baldness.