158 citations
,
November 1998 in “Cell” β-catenin affects hair growth and can lead to tumors, needing more research for better understanding.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
August 2023 in “Research Square (Research Square)” Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
11 citations
,
June 2012 in “Journal of Dermatological Science” Scientists identified a group of human skin cells with high growth and regeneration potential.
10 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
9 citations
,
January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
December 2024 in “Research Square (Research Square)” Placental stem cell exosome therapy improves hair growth and reduces hair loss.
January 2023 in “Postępy Dermatologii i Alergologii” Stem cells can improve wound healing, reduce scars, promote hair growth, rejuvenate skin, and enhance fat grafts in plastic surgery, but there are still some concerns.
6 citations
,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
480 citations
,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
9 citations
,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
February 2024 in “Biomedical materials” Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
September 2019 in “Journal of Investigative Dermatology” Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
5 citations
,
August 2020 in “Curēus” The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.
37 citations
,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
24 citations
,
October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
132 citations
,
August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
11 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
6 citations
,
May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
40 citations
,
December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
February 2026 in “BMC Plastic and Reconstructive Surgery” Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
9 citations
,
March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
36 citations
,
January 2021 in “Frontiers in Cell and Developmental Biology” Hypoxia and epigenetics are crucial for cell growth and tissue regeneration.
3 citations
,
April 2019 in “Stem cells international” Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
300 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.