40 citations
,
January 2018 in “Pharmaceutics” Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
39 citations
,
January 2013 in “Journal of Investigative Dermatology” Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
39 citations
,
March 2009 in “Dermatology Online Journal” Understanding EGFR roles could lead to new hair loss treatments.
39 citations
,
March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
35 citations
,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
30 citations
,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
27 citations
,
August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
26 citations
,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
25 citations
,
June 2021 in “Developmental Cell” Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
25 citations
,
May 2013 in “Journal of mammary gland biology and neoplasia” Hedgehog signaling is crucial for mammary gland development over hair follicles.
25 citations
,
September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
17 citations
,
June 2019 in “The journal of immunology/The Journal of immunology” A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
17 citations
,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
16 citations
,
July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
15 citations
,
January 1995 in “Archives of dermatological research” OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.
12 citations
,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
9 citations
,
December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
8 citations
,
June 2019 in “Pharmaceutical research” Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.
8 citations
,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
5 citations
,
May 2020 in “Pharmaceutical Research” Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
4 citations
,
February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
4 citations
,
October 2018 in “Cell Stem Cell” Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.
4 citations
,
July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
3 citations
,
February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
3 citations
,
June 2020 in “Developmental Cell” Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
3 citations
,
February 2005 in “Aktuelle Dermatologie” Prolactin and TGF-β receptor blockers might help treat hair loss.
2 citations
,
September 2023 in “PLoS biology” Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.