Hair bulb cells can create skin-like tissues for potential skin repair.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
9 citations
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March 1987 in “British Journal of Dermatology” EGF and FGF can boost hair growth by speeding up cell growth.
September 2019 in “Journal of Investigative Dermatology” IL-17 and certain immune cells are linked to more severe alopecia areata.
291 citations
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October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
33 citations
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March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
30 citations
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April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
January 2006 in “Chinese Journal of Dermatology” Mesenchymal cells are essential for hair follicle stem cell growth.
January 2003 in “Journal of the Fourth Military Medical University” Hair follicles can regenerate if cut at certain points, with stem cells in the upper part.
130 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
57 citations
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November 1998 in “Wound Repair and Regeneration” Hair papilla cells can create and regenerate hair bulbs under the right conditions.
22 citations
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July 1990 in “Acta Dermato Venereologica” High levels of testosterone and dihydrotestosterone inhibit hair cell growth, while high levels of estradiol promote it.
46 citations
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November 1998 in “Experimental Cell Research” K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
April 2017 in “Journal of Investigative Dermatology” Scientists created a tiny, 3D model of a hair follicle that grows and acts like a real one.
45 citations
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December 2004 in “Forensic Science International” Laser microdissection helps get DNA from single hair follicles for better forensic analysis.
19 citations
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November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
January 2011 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” New molecules can prevent cell death in hair follicles.
14 citations
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October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
Activating certain cells in hair follicles can prevent hair loss caused by cancer treatments.
15 citations
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September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
5 citations
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February 2007 in “Cytology and genetics” Gene expression regulates keratin production for normal hair growth.
8 citations
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March 2009 in “Differentiation” Adult vibrissa follicle stem cells can regenerate hair follicles, glands, and skin.
September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
Testosterone and dihydrotestosterone can slow down the growth of certain hair follicle cells.
December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.
36 citations
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November 1990 in “The Journal of Dermatology” Dermal papillae enhance hair follicle growth and structure.
Activating certain hair follicle cells could prevent hair loss from cancer treatments.
57 citations
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April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
46 citations
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April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.