research The Harmonies Played by TGF-β in Stem Cell Biology
TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
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810-840 / 1000+ results research Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity
Hair follicle stem cells are controlled by their surrounding environment.
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
research Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning
Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
research Two‐photon microscopy for intracutaneous imaging of stem cell activity in mice
Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
research Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration
Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
research The amazing miniorgan: Hair follicle
Understanding hair follicles can lead to new treatments for hair loss and skin tumors.
research The hair follicle as a neuro-immuno-endocrine organ: Implications in hair disorders and regenerative therapies
Understanding hair follicle signaling can improve hair disorder treatments.
research Cholesterol promotes hair growth through activating sympathetic nerves and enhancing the proliferation of hair follicle stem cells
Cholesterol helps hair grow by activating nerves and boosting hair follicle stem cells.
research Stem Cell Therapy in Androgenetic Alopecia: A Review of Dermatology Literature from 2012-2022
Stem cell therapy shows promise for treating hair loss in androgenetic alopecia.
research The balance of Bmp6 and Wnt10b regulates the telogen-anagen transition of hair follicles
BMP6 and Wnt10b control whether hair follicles are resting or growing.
research Comparisons of mouse models for hair follicle reconstitution
The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
research Exposure to 50 Hz electromagnetic fields enhances hair follicle regrowth in C57BL/6 mice
Exposure to 50 Hz electromagnetic fields may help mice grow hair faster.
research RORA Regulates Autophagy in Hair Follicle Stem Cells by Upregulating the Expression Level of the Sqstm1 Gene
RORA boosts autophagy in hair follicle stem cells, potentially aiding hair growth.
research In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells
Araliadiol may promote hair growth like minoxidil without being toxic.
research Light-Emitting Hair Follicles: Studying Skin Regeneration With In Vivo Imaging
Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.
research MicroRNA-149-Mediated MAPK1/ERK2 Suppression Attenuates Hair Follicle Stem Cell Differentiation
Increasing miR-149 reduces hair follicle stem cell growth and hair development by affecting certain cell growth pathways.
research miR-27a Targeting PIK3R3 Regulates the Proliferation and Apoptosis of Sheep Hair Follicle Stem Cells
Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.
research Aging, alopecia, and stem cells
The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.
research Stem cells and the circadian clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research Short-Term Clinical Assessment of Treating Female Androgenic Alopecia with Autologous Stem Cells Derived from Human Hair Follicles
Using stem cells from hair follicles to treat female hair loss is safe and effective after six months.
research Lef1 Contributes to the Differentiation of Bulge Stem Cells by Nuclear Translocation and Cross-Talk with the Notch Signaling Pathway
Lef1 helps stem cells become hair cells by interacting with specific signaling pathways.
research Sustained Human Hair Follicle Growth Ex Vivo in a Glycosaminoglycan Hydrogel Matrix
Human hair grows better in a special gel that mimics skin.
research Progeny of Lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis
research Local and systemic mechanisms that control the hair follicle stem cell niche
research Future Directions: The Known and Unknown Roles of Hair-Follicle Stem Cell Types
research CD44 signaling in skin wound healing and regeneration
CD44 signaling can help heal wounds without scars.
research Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation
Sebaceous glands can form new hair follicles when activated, but hair follicle bulges cannot.
research Expression of the hair stem cell-specific marker nestin in epidermal and follicular tumors.
Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.