GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
Glypican-1 is important for hair follicle blood vessel growth and could be a target for treating hair loss.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
6 citations
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September 2019 in “Skin pharmacology and physiology” RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
17 citations
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September 2016 in “Stem cells translational medicine” Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
1 citations
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May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
20 citations
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August 2005 in “Journal of Cutaneous Pathology” The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
130 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
13 citations
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April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
86 citations
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June 1998 in “Journal of Investigative Dermatology” The hairless gene mutation causes baldness by disrupting hair follicle structure.
1 citations
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January 2005 in “Experimental Dermatology” MC-1R in skin cells may influence inflammation and collagen production.
June 2023 in “Animal Bioscience” Vimentin and transthyretin proteins are linked to black coat color in sheep.
January 2019 in “대한피부과학회지” Metformin promotes hair growth by affecting cell growth and protein signaling related to hair growth.
Low-level light therapy can promote hair growth by stimulating cell interactions in hair follicles.
A skin model using hair and skin cells can mimic human skin for research.
January 2005 in “日本機械学會論文集. C編” Minoxidil sulfate and pinacidil promote hair growth likely by increasing blood flow, not by activating K channels.
May 2002 in “Journal of Investigative Dermatology” New findings on hair keratin, wound healing, and skin blistering were presented.
1 citations
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September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
4 citations
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January 2004 in “Biological and Pharmaceutical Bulletin” AgK114 protein helps in hamster skin injury recovery.
KRTAP6 genes affect wool quality in sheep.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.
January 2026 in “Open MIND” Fibroblasts play a key role in hair loss by affecting hair growth and causing inflammation.
March 2022 in “Benha Journal of Applied Sciences” ULBP3 levels are higher in Tinea capitis patients and may help predict the disease's severity.
July 2020 in “Experimental Dermatology” Aging causes hair thinning in women due to changes in the scalp environment.
May 2015 in “Hair transplant forum international” Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.
6 citations
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January 1994 in “Skin Pharmacology and Physiology” Dermal papillae are crucial for hair growth and follicle development.
October 2025 in “Journal of Investigative Dermatology” Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.
56 citations
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December 1990 in “Differentiation” Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.
14 citations
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February 2011 in “Experimental dermatology” A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.