100 citations
,
November 1996 in “Molecular Medicine Today” Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
91 citations
,
May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
88 citations
,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
86 citations
,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
81 citations
,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
66 citations
,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
65 citations
,
September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
57 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
52 citations
,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
35 citations
,
May 2019 in “Frontiers in genetics” Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.
26 citations
,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
25 citations
,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
25 citations
,
August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
24 citations
,
October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
16 citations
,
March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
14 citations
,
January 2016 in “Biochemical and Biophysical Research Communications” Ginsenoside Re from ginseng may help hair grow by blocking a specific growth-inhibiting pathway.
10 citations
,
January 2016 in “PLOS ONE” Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
9 citations
,
July 2011 in “Scientific Reports” Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.
5 citations
,
November 2015 in “International Journal of Radiation Biology” Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
3 citations
,
June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
1 citations
,
August 2019 in “Research Square (Research Square)” Cashmere goats have a hair growth cycle with specific genes regulating growth, regression, and resting periods.
May 2020 in “Research Square (Research Square)” Researchers found four key stages of cell development that are important for hair growth and shedding in cashmere goats.
40 citations
,
December 2011 in “British Journal of Dermatology” Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
212 citations
,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
74 citations
,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
6 citations
,
November 2010 in “Histochemistry and cell biology” The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
38 citations
,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.