28 citations
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January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
26 citations
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December 2020 in “Genes” A combination of IGF-1 and EGF promotes hair growth in Angora rabbits.
23 citations
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August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
23 citations
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May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
23 citations
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June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
21 citations
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June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
20 citations
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August 2005 in “Journal of Cutaneous Pathology” The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
20 citations
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January 2008 in “Journal of Korean Medical Science” NGAL may help maintain skin balance and is linked to skin disorders and cancers.
19 citations
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June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
18 citations
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April 2016 in “Molecular Genetics and Genomics” Thymosin beta 4 may help hair growth and could be a treatment for hair issues.
17 citations
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January 2014 in “Stem Cells Translational Medicine” Canine epidermal neural crest stem cells could be a promising treatment for spinal cord injuries in dogs.
17 citations
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June 2020 in “British Journal of Dermatology” Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.
16 citations
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January 2020 in “Diabetes” A new therapy sped up wound healing and reduced scarring in diabetic rats.
16 citations
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September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
16 citations
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July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
16 citations
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December 2016 in “Molecular Medicine Reports” Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
16 citations
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September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
11 citations
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June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
10 citations
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January 2010 in “Acta Histochemica Et Cytochemica” c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.
10 citations
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January 2018 in “Elsevier eBooks” Burn scars heal abnormally and more research is needed to find better treatments.
9 citations
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December 2002 in “Novartis Foundation Symposium” LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
7 citations
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May 1978 in “International Journal of Dermatology” Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
6 citations
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January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
6 citations
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January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.
5 citations
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April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
5 citations
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August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
5 citations
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September 2018 in “Acta histochemica” The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.
4 citations
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December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
4 citations
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May 2018 in “Electronic Journal of Biotechnology” All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.
3 citations
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.