Dermal stem cells help regenerate hair follicles and heal skin wounds.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
305 citations
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June 2012 in “Nature” Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
192 citations
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March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
103 citations
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November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
77 citations
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July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
70 citations
,
December 2004 in “Differentiation” The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
61 citations
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September 2020 in “Bioactive Materials” A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.
39 citations
,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
39 citations
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
35 citations
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February 2015 in “Experimental Dermatology” Cells from the base of hair follicles help blood vessel cells survive and grow, which is important for healthy hair.
33 citations
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September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
31 citations
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October 2016 in “PLoS ONE” The ubiquitin-mediated proteolysis pathway is crucial for hair follicle development in cashmere goats.
25 citations
,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
25 citations
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April 2018 in “Electromagnetic biology and medicine” Mobile phone radiation may cause DNA damage in human ear hair follicle cells.
25 citations
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May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
22 citations
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December 2013 in “Molecular biology of the cell” ILK is essential for proper hair follicle development and structure.
20 citations
,
May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
14 citations
,
June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
8 citations
,
May 2021 in “Applied Materials Today” New nano composite helps reduce scars and regrow hair during burn wound healing.
6 citations
,
September 2024 in “Frontiers in Physiology” Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
3 citations
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October 2020 in “Internatuinal Journal of Radiation Research” Gamma irradiation can stimulate hair growth by promoting new blood vessel formation.
3 citations
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January 2018 in “Chiang Mai University Journal” Centella asiatica extract may help promote hair growth.
3 citations
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July 2015 in “European Journal of Dermatology” AGEs may cause hair loss by increasing inflammation in hair follicles.
2 citations
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May 2015 in “PloS one” Hair follicle pores help cell survival and growth, even after radiation.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
1 citations
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November 2002 in “Journal of dermatology” The antibody created from BCC tissues reacts similarly to both BCC and hair follicles, suggesting BCC may come from hair follicle cells.
1 citations
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January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.