25 citations
,
March 2014 in “Experimental Dermatology” Leptin helps start the growth phase of hair.
13 citations
,
October 2010 in “Methods in molecular biology” Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
11 citations
,
July 2017 in “Regenerative Medicine” The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.
10 citations
,
January 2004 in “PubMed” Radiation increases cell death in hair follicles, but certain treatments can protect against this effect.
8 citations
,
April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
3 citations
,
April 2009 in “PubMed” Melatonin may protect rat hair follicles from damage caused by oxidative stress after a burn.
2 citations
,
July 2022 in “Cell Regeneration” Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
1 citations
,
June 2023 in “Journal of Cosmetic Dermatology” Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.
June 2025 in “Electronic Journal of General Medicine” Melatonin may help regrow hair, but more consistent research is needed.
January 2025 in “Molecules” Caffeine may help with hair loss, but more research is needed to confirm its effectiveness.
October 2024 in “Dermatologic Surgery” Exosomes might help with hair loss, but more research is needed to confirm their safety and effectiveness.
August 2023 in “Dermatologic Surgery” Wounding may stimulate hair growth, but more research is needed to confirm the safety and effectiveness of related treatments.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
September 2007 in “PubMed” Implanted human scalp cells can regenerate hair-like structures in mice.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
September 2011 in “Clinical Biochemistry” Certain sugars increase in some layers of the hair follicle during the middle of the healing process in rats, which may help improve healing.
Diabetes might contribute to hair loss, but more research is needed.
25 citations
,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
1 citations
,
July 2019 in “Journal of Dermatology and Dermatologic Surgery” Stem cell therapy shows promise for hair loss treatment, but more research is needed to confirm its effectiveness.
218 citations
,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
142 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
121 citations
,
March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
96 citations
,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
77 citations
,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
77 citations
,
February 2001 in “Journal of Dermatological Science” HGF activator helps convert HGF to its active form, promoting hair growth.
44 citations
,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
34 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Gene therapy shows promise for treating hair loss by targeting hair follicles.
27 citations
,
August 2018 in “Therapeutic Delivery” Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.