April 2026 in “Indian Dermatology Online Journal” Premature graying of hair is more common in males and linked to family history, smoking, hair plucking, and low levels of certain vitamins and minerals.
16 citations
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January 2018 in “International journal of trichology” Genetics and nutritional deficiencies are key factors in premature graying of hair.
April 2025 in “Dermatology Practical & Conceptual” Increased LC3 gene expression may be linked to premature graying of hair.
1 citations
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April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
75 citations
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January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
2 citations
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January 1997 in “Mapping” Gambogic Amide may prevent hair greying and promote hair growth by maintaining hair pigmentation.
45 citations
,
June 2012 in “JRSM Cardiovascular Disease” Young Indians with coronary artery disease often have risk factors like smoking and central obesity, and cutaneous markers should be monitored for lifestyle changes.
114 citations
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October 2006 in “Journal of the European Academy of Dermatology and Venereology” The new clobetasol propionate foam is effective and safe for treating alopecia areata.
December 2008 in “Enzyme and Microbial Technology” New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
260 citations
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June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
Premature graying of hair is linked to vitamin D and B12 deficiencies, thyroid issues, iron imbalance, stress, and lifestyle habits, and affects quality of life.
1 citations
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September 2019 in “Journal of cosmetic dermatology” Lead and selenium levels don't cause premature graying.
1 citations
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December 2017 in “The Medical journal of Basrah University” People with metabolic syndrome get gray hair earlier.
20 citations
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January 2016 in “International journal of trichology” Young Indians with premature graying often have lower levels of certain nutrients and unhealthy lifestyles.
May 2026 in “Archives of Dermatological Research” Genetics likely cause premature graying hair, not vitamin levels.
September 2022 in “International Journal of Trichology” Trichoscopic measurements help determine the severity of female pattern hair loss.
1 citations
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February 2022 in “Open Access Macedonian Journal of Medical Sciences” Low zinc levels might contribute to early hair graying.
35 citations
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January 2013 in “International Journal of Trichology” Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.
26 citations
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October 2011 in “Biological trace element research” Low copper levels might cause premature graying of hair.
17 citations
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January 2018 in “International Journal of Trichology” Low levels of iron, copper, and calcium may contribute to premature hair graying.
7 citations
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January 2018 in “PubMed” Low levels of iron, copper, and calcium may cause early hair graying.
1 citations
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October 2020 in “Journal of Cosmetic Dermatology” Low iron levels are linked to premature graying of hair, but vitamin D levels are not.
Good nutrition may help prevent premature hair graying.
October 2021 in “QJM: An International Journal of Medicine” Low iron levels are linked to premature graying of hair, but vitamin D levels are not.
May 2021 in “Open Access Macedonian Journal of Medical Sciences” People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
June 2026 in “International Journal of Drug Delivery Technology” Herbal remedies show promise for managing premature hair greying but need more research.
November 2025 in “Journal of Cosmetic Dermatology” Exosome therapy can safely and effectively restore color to gray hair.
1 citations
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October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
November 2022 in “International Journal of Pharmaceutical and Bio-Medical Science” The herbal hair oil may improve hair shine and address hair issues, but its effectiveness is unclear.