4 citations
,
October 2019 in “Skin Appendage Disorders” Gefitinib can cause hair and eyebrow darkening.
30 citations
,
June 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Oral zinc sulphate reduces dark hair color in mice.
16 citations
,
February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
31 citations
,
February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.
1 citations
,
January 2013 in “Nasza Dermatologia Online” Vitamin B12 deficiency can cause reversible hair color loss in children.
2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.
1 citations
,
January 2021 in “Journal of Dermatology and Dermatologic Surgery” Taking Vitamin D supplements may increase the risk of skin darkening after laser hair removal.
January 2018 in “Acta dermato-venereologica” April 2015 in “Dentistry 3000” Premature hair graying in the face may be influenced by genetics and environment.
77 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
11 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
15 citations
,
July 2004 in “AIDS” Indinavir therapy can cause reversible skin, hair, and nail darkening.
150 citations
,
April 1997 in “Journal of Investigative Dermatology”
23 citations
,
April 1999 in “Dermatologic Clinics” Pulsed-intense light can significantly reduce hair, with effectiveness depending on treatment number and timing, and has mild side effects.
9 citations
,
November 2015 in “JAMA dermatology” A 91-year-old woman's hair turned black in one spot, with skin changes underneath.
2 citations
,
October 2021 in “Clinical and experimental dermatology” Cyperus rotundus essential oil effectively treats underarm darkening, reduces inflammation, and slows hair growth.
December 2022 in “Gastroenterology” A man with Cronkhite-Canada syndrome improved significantly with immunosuppressive therapy.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
April 2019 in “Journal of the Dermatology Nurses’ Association” A 37-year-old man with hair loss and skin issues was successfully treated with oral antibiotics, highlighting the need for early treatment. Long-term care includes low-dose antibiotics and avoiding caps and wigs.
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.
67 citations
,
October 1997 in “Dermatologic Surgery” The EpiLight Hair Removal System removed about 60% of hair with some side effects, and more research is needed to confirm long-term effectiveness.
21 citations
,
March 2020 in “Journal of lasers in medical sciences” Diode laser hair removal is effective and safe, but side effects vary by ethnicity and treatment number.
21 citations
,
January 2007 in “Journal of Drugs in Dermatology” The laser effectively removes hair for skin types IV and V but is less effective for type VI.
9 citations
,
June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
9 citations
,
March 2005 in “Aesthetic surgery journal” The long-pulse alexandrite laser effectively removes hair permanently.
8 citations
,
May 2004 in “Facial plastic surgery clinics of North America” Laser hair removal is now more effective, but the best treatment schedule is still uncertain.
5 citations
,
January 2021 in “Daru” A woman had severe reactions to methotrexate, including skin issues and organ problems, but improved after 38 days in the hospital.
5 citations
,
October 2012 in “Veterinary Pathology” A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.
3 citations
,
September 2017 in “Pediatric Dermatology” Avoiding allergens can improve skin and hair conditions in adults with allergic reactions.
2 citations
,
July 2020 in “Journal of Applied Pharmaceutical Science” Natural ingredients can improve skin and hair, but more research is needed.