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GlossaryHair Loss Regression

previously lost hair begins to grow back

Hair Loss Regression, also known as Hair Loss Reversal, refers to the process where previously lost hair begins to grow back, often due to treatments or changes in underlying conditions. This can occur through various methods such as medication (e.g., minoxidil or finasteride), lifestyle changes, or medical procedures like hair transplants. The term is significant in both clinical and cosmetic contexts, as it indicates a positive response to interventions aimed at combating alopecia.

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Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla

research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla

92 citations , June 2005 in “Journal of Investigative Dermatology”

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Exhaustive Analysis of Scalp Hair Regression: Subjective and Objective Perception from Initial Hair Loss to Severe Miniaturization and Drug-Induced Regrowth

research Exhaustive analysis of scalp hair regression: subjective and objective perception from initial hair loss to severe miniaturisation and drug-induced regrowth

3 citations , January 2021 in “Plastic and Aesthetic Research”

Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.

research Effect of Behavioral Factors on Severity of Female Pattern Hair Loss: An Ordinal Logistic Regression Analysis

2 citations , January 2020 in “International Journal of Medical Sciences”

Avoid alcohol, ponytails, and oily scalp, and get good sleep to prevent severe hair loss.

research Mimicking Senescence Factors to Characterize the Mechanisms Responsible for Hair Regression and Hair Loss: An In Vitro Study

July 2025 in “Organoids”

TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.

Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

128 citations , March 2006 in “American Journal of Pathology”

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

research p53 Involvement in the Control of Murine Hair Follicle Regression

71 citations , June 2001 in “American Journal of Pathology”

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22

research Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22

52 citations , May 2015 in “PLOS Genetics”

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia

research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia

47 citations , April 2000 in “The American journal of pathology”

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

research Intercellular Adhesion Molecule-1 and Hair Follicle Regression

29 citations , April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

ICAM-1 helps regulate hair growth cycles and skin remodeling.

research Association of Risk Factors with Female Pattern Hair Loss

May 2024 in “Medicine today”

Older age, family history, and low iron levels increase the risk of female hair loss.

Hair Loss in Women: A Study at Sheffield Royal Infirmary (1959-1966)

research HAIR LOSS IN WOMEN

39 citations , October 1967 in “British Journal of Dermatology”

Hair loss in women often doesn't follow a pattern, isn't linked to age, may be genetic, and can be related to thyroid issues or other health factors.

research Acute hair loss on the limbs in frontal fibrosing alopecia: a clinicopathological study of two cases

31 citations , April 2010 in “British journal of dermatology/British journal of dermatology, Supplement”

Frontal fibrosing alopecia can cause sudden hair loss on limbs, similar to scalp hair loss.

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

193 citations , August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression

2 citations , February 2019 in “Journal of Investigative Dermatology”

Higher levels of the DP2 receptor may lead to hair loss.

research Zinc Status in Kurdish Adults With Hair Loss

August 2024 in “Cureus”

Maintaining enough zinc may help prevent and manage hair loss.

Female Hair Loss: Assessment, Categorization, and Management

research Female hair loss

July 2019 in “InnovAiT”

The document concludes that diagnosing female hair loss requires careful examination, with treatments varying by condition and psychological support often necessary.

research PLOS Science Wednesday: Hi Reddit, I'm Zhengquan Yu, here to talk about my recent PLOS Genetics paper that has identified the key role of a microRNA in hair loss. I'm joined by Maksim Plikus, who studi

September 2015

MicroRNA miR-22 causes hair loss by making hair follicles regress early.

Efficacy of an Oral Ageratum Conyzoides Formulation on Increasing Hair Growth and Decreasing Hair Loss in Males and Females: A Randomised Double-Blind Placebo-Controlled Study

research Efficacy of an Oral Ageratum Conyzoides Formulation on Increasing Hair Growth and Decreasing Hair Loss in Males and Females: A Randomised Double-Blind Placebo-Controlled Study

June 2023 in “Trichology and cosmetology:”

Ageratum Conyzoides, when taken orally, can effectively reduce hair loss and improve hair growth.

research Prevalence of Hair Loss among Men and its Association with Smoking and Stress: A Case Study in the City of Lahore, Pakistan

June 2021 in “Pakistan Journal of Medical and Health Sciences”

The study found no link between hair loss, stress, and smoking among men in Lahore.

Sanguisorba Officinalis Root Extract Has FGF-5 Inhibitory Activity and Reduces Hair Loss by Prolonging the Anagen Period

research Sanguisorba Officinalis Root Extract Has FGF-5 Inhibitory Activity and Reduces Hair Loss by Causing Prolongation of the Anagen Period

3 citations , January 2007 in “Nishinihon hifuka/Nishi Nihon hifuka”

Great Burnet extract may prevent hair loss by extending the hair growth phase.

research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview

1 citations , December 2023 in “Biomolecules”

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

research Aromatase inhibitors induce ‘male pattern hair loss’ in women?

19 citations , May 2013 in “Annals of Oncology”

Aromatase inhibitors cause male pattern hair loss in women.

research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation

321 citations , January 2012 in “Cell stem cell”

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

research Anti-Hair Loss Potential of Perilla Seed Extracts: In Vitro Molecular Insights from Supercritical Fluid Extraction

July 2025 in “Foods”

Perilla seed extract may help prevent hair loss better than some standard treatments.

research Short anagen hair syndrome is caused by mutations in the WNT10A gene and has a genetic overlap with male pattern hair loss

November 2023 in “British Journal of Dermatology”

Mutations in the WNT10A gene cause Short Anagen Hair syndrome and increase the risk of male pattern hair loss.

Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation

research Hair organ regeneration via the bioengineered hair follicular unit transplantation

66 citations , May 2012 in “Scientific Reports”

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

research p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen)

24 citations , January 2003 in “Journal of Investigative Dermatology”

Blocking a specific receptor slows down hair loss in mice.

research Many Paths to Alopecia via Compromised Regeneration of Hair Follicle Stem Cells

8 citations , May 2013 in “Journal of Investigative Dermatology”

Different problems with hair stem cell renewal can lead to hair loss.

research Hair Pathology

1 citations , July 2018 in “Elsevier eBooks”

Triple horizontal scalp biopsies are 98% accurate in diagnosing hair loss, better than single biopsies.

research Frontotemporal hairline recession in a postmenopausal woman

3 citations , April 2015 in “Dermatology practical & conceptual”

Postmenopausal women can experience hairline recession, affecting their quality of life, and more research is needed for treatments.