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research Role of genetics and sex steroid hormones in male androgenetic alopecia and female pattern hair loss: An update of what we now know

87 citations , March 2011 in “Australasian Journal of Dermatology”

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

research Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function

74 citations , June 2018 in “Cell death and disease”

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

research Management of Hair Loss

74 citations , April 2005 in “Dermatologic Clinics”

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

research The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study

70 citations , February 2017 in “Dermatologic Surgery”

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

research Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?

62 citations , January 2013 in “Skin Pharmacology and Physiology”

Low iron and vitamin D levels are linked to hair loss in women.

research Stem cell plasticity enables hair regeneration following Lgr5+ cell loss

56 citations , May 2017 in “Nature Cell Biology”

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

research Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss

54 citations , December 2014 in “Wound Repair and Regeneration”

PRP injections may improve hair thickness and density in female hair loss patients.

research Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss

46 citations , October 1999 in “Journal of The American Academy of Dermatology”

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

research Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy

32 citations , August 2019 in “Nature Communications”

Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.

Selected Variants of the Steroid-5-Alpha-Reductase Isoforms SRD5A1 and SRD5A2 and the Sex Steroid Hormone Receptors ESR1, ESR2, and PGR: No Association with Female Pattern Hair Loss Identified

research Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified

18 citations , February 2012 in “Experimental Dermatology”

No link found between specific genes and female pattern hair loss.

research Nonsurgical Therapy for Hair Loss

14 citations , August 2013 in “Facial Plastic Surgery Clinics of North America”

Some nonsurgical hair loss treatments are effective, especially if started early.

research Methods of hair loss evaluation: a comparison of TrichoScan^®with the modified wash test

14 citations , May 2013 in “Experimental Dermatology”

The modified wash test is better than TrichoScan® for diagnosing hair loss.

Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

research Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing

11 citations , November 2012 in “Seminars in Cutaneous Medicine and Surgery”

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

Comparison Between Single- Versus Double-Spin Prepared Platelet-Rich Plasma Injection in Treatment of Female Pattern Hair Loss: Clinical Effect and Relation to Vascular Endothelial Growth Factor

research Comparison between single- versus double-spin prepared platelet-rich plasma injection in treatment of female pattern hair loss: clinical effect and relation to vascular endothelial growth factor

10 citations , September 2020 in “Archives of Dermatological Research”

Both methods improve hair density and thickness; double-spin may be more effective.

research Controversy: is there a role for adjuvants in the management of male pattern hair loss?

10 citations , January 2010 in “PubMed”

Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.

research Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation‐induced canities

7 citations , July 2020 in “Pigment cell & melanoma research”

RT1640 treatment reverses gray hair and promotes hair growth in mice.

research The role of photobiomodulation when associated with microneedling in female pattern hair loss

7 citations , March 2019 in “Medicine”

Combining light therapy and microneedling shows promise for treating female hair loss.

research Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions toward Clinical Reality

6 citations , February 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.

research Understanding Causes of Hair Loss in Women

4 citations , May 2021 in “Dermatologic Clinics”

The conclusion is that hair loss in women is caused by a mix of hormonal, environmental, and genetic factors, and treatments should target these various causes.

research MiR-92a-1-5p and miR-328-3p Are Up-Regulated in Skin of Female Pattern Hair Loss Patients

4 citations , January 2019 in “Annals of Dermatology”

Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.

research Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles

4 citations , January 2014 in “The Scientific World Journal”

Red deer antler extract helps hair grow by extending the growth phase and increasing cell growth in hair follicles.

research Hormonal treatment for male-pattern hair loss: implications for cancer of the prostate?

4 citations , October 2002 in “BJUI”

Finasteride treats hair loss but may affect prostate cancer detection.

research Clinical Patterns of Hair Loss in Men

3 citations , May 2021 in “Dermatologic Clinics”

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

Standardization of Plasma Rich in Growth Factors and Its Effects on Androgenic Hair Loss

research Standardization of Plasma Rich in Growth Factors (PRGF) and its effects on androgenic hair loss

3 citations , December 2019 in “Journal of Cosmetic and Laser Therapy”

PRGF treatments increased hair number and thickness in people with hair loss, with more injections leading to better results.

Autophagy-Related Protein 12 Associates With Anti-Apoptotic B Cell Lymphoma-2 to Promote Apoptosis in Gentamicin-Induced Inner Ear Hair Cell Loss

research Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss

2 citations , April 2017 in “Molecular Medicine Reports”

Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.

research Alternative Medicine for Hair Loss

1 citations , May 2017 in “InTech eBooks”

Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.

research 841 Minoxidil dose response study in female pattern hair loss patients determined to be non-responders to 5% topical Minoxidil

1 citations , April 2017 in “Journal of Investigative Dermatology”

Higher minoxidil dose helps hair growth in non-responders without side effects.

research Diagnosis and management of hair loss in children

1 citations , May 2016 in “Current Opinion in Pediatrics”

Children's hair loss can be caused by various factors and should be treated with appropriate, age-specific methods and psychological support.

research Association between hair loss and cardiometabolic diseases in Chinese adults: a cross-sectional analysis in Tianning Cohort

January 2026 in “Journal of Epidemiology”

This cross-sectional study of 5,020 Chinese adults from the Tianning cohort found that severe hair loss is associated with higher odds of hypertension, diabetes, and cardiometabolic multimorbidity (CMM), but not dyslipidemia. Specifically, individuals with severe hair loss had 48% higher odds of hypertension and 44% higher odds of diabetes. The associations were more pronounced in adults under 55 years and in women, suggesting shared hormonal and vascular mechanisms. Despite limitations such as potential residual confounding and the use of visual assessment scales, the study highlights the need for attention to cardiometabolic health in individuals with significant hair loss and suggests that hair loss may be an indicator of cardiometabolic health risks.

research Enhanced stratification of male pattern hair loss using AI through novel loss region ratio analysis

November 2025 in “Scientific Reports”

AI improves accuracy and consistency in diagnosing male pattern hair loss.

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