February 2025 in “Journal of Investigative Dermatology” The ZIP13 variant is linked to abnormal hair quality.
January 2025 in “International Journal of Trichology” Loose anagen hair syndrome in children often resolves on its own.
178 citations
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October 2001 in “Genes & Development” The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.
May 2020 in “International journal of molecular biology” Mutations in the AR gene cause hair thinning and loss.
May 2023 in “International journal of science and research” 2% minoxidil solution improved hair density and quality in children with Loose Anagen Hair Syndrome.
4 citations
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December 2016 in “Blood” A new gene mutation may cause cyclic thrombocytopenia by affecting platelet production.
20 citations
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January 2009 in “International Journal of Dermatology” Hair loss in Clouston's syndrome improved with minoxidil and tretinoin treatment.
August 2013 in “Fertility and Sterility” Hair loss is common in women with PCOS and is linked to symptoms like acne and excess hair but not to worse metabolic health.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Hair loss is mainly due to genes and hormones, and can be treated with minoxidil and finasteride. Excessive hair growth is linked to certain disorders and can be managed with hormonal therapy and laser hair removal.
34 citations
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January 2014 in “Indian Dermatology Online Journal” Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
13 citations
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November 2015 in “Blood Pressure” Hair loss may indicate higher heart risk and metabolic issues.
January 2024 in “The Egyptian Journal of Hospital Medicine ” Hair loss may indicate a higher risk of heart disease and other health issues related to metabolism.
April 2023 in “Nigerian Journal of Clinical Practice” Hair loss in adults is linked to heart disease risk factors like unhealthy blood fats, lack of exercise, and alcohol use. It's also slightly more common in people with metabolic syndrome. As people age, hair loss gets worse. In men, severe hair loss is tied to high blood pressure and a larger waist. In women, it's tied to higher body weight. People with hair loss should be checked for unhealthy blood fats and advised to avoid alcohol and inactivity.
July 2022 in “medRxiv (Cold Spring Harbor Laboratory)” Satoyoshi syndrome is likely an autoimmune disease that mainly affects young women and improves with immune-related treatments.
95 citations
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November 2016 in “Journal of The American Academy of Dermatology” Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.
2 citations
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August 2014 in “Journal of The American Academy of Dermatology” Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.
April 2021 in “Medical Science and Discovery” Early hair loss in men may signal broader health issues similar to PCOS in women.
42 citations
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September 2003 in “Journal of Investigative Dermatology” A missing mK6irs1 gene causes hair loss in mice.
37 citations
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April 2012 in “British Journal of Dermatology” Female hair loss linked to metabolic syndrome, not in males.
16 citations
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January 2014 in “International Journal of Trichology” Early hair loss links to metabolic issues in young Indian men.
4 citations
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May 2014 in “European Journal of Dermatology” Severe hair loss links to metabolic issues in older men with psoriasis.
2 citations
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November 2017 in “International Journal of Research in Dermatology” Premature hair loss doesn't increase the risk of metabolic syndrome.
December 2022 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” Early hair loss in young men is linked to higher risk of metabolic syndrome.
November 2022 in “Frontiers in Medicine” Severe hair loss in Chinese men is linked to high blood pressure, while in women, it's linked to larger waist size and cholesterol issues.
47 citations
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June 2016 in “JAMA Dermatology” Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.
October 2023 in “Siriraj Medical Journal” Acne and hair loss in women can greatly lower their quality of life, but having polycystic ovarian syndrome does not.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” Current treatments for common male hair loss have limited effectiveness and can cause side effects.
January 2019 in “Elsevier eBooks” Different hair disorders have specific treatments and outcomes, with some resolving on their own and others requiring medication or emotional support.
March 2014 in “Journal of The American Academy of Dermatology” Azathioprine may help with severe hair loss, a new topical treatment could counteract hair thinning, and trichoscopy can diagnose hair-pulling disorder effectively.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” Acne and hair loss are not good indicators of hormone imbalance in PCOS, but excessive body hair is.