May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of TET2 increases the risk of skin and oral cancer.
1308 citations
,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
45 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Understanding hair follicles through various models can help develop new treatments for hair disorders.
24 citations
,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
16 citations
,
July 2019 in “Biochemical and Biophysical Research Communications” CD36-expressing dermal sheath cells help form blood vessels in hair follicles, aiding hair growth.
2 citations
,
August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
June 2026 in “International Journal of Homoeopathic Sciences” Understanding hair loss causes can improve treatments and quality of life.
December 2024 in “Journal of Cosmetic Dermatology” Oral minoxidil rarely causes pericardial effusion, especially at low doses.
421 citations
,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
32 citations
,
June 2000 in “Dermatologic Surgery” Different factors help diagnose and treat hair loss accurately.
5 citations
,
February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
May 2023 in “Pharmaceuticals” Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
March 2019 in “Journal der Deutschen Dermatologischen Gesellschaft” Rothmund-Thomson syndrome type 2 can cause chronic, poorly healing wounds.
80 citations
,
April 2006 in “Clinical Interventions in Aging” Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
71 citations
,
January 2012 in “PloS one” The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.
40 citations
,
January 2017 in “Intestinal Research” Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
November 2025 in “International Journal of Recent Innovations in Medicine and Clinical Research” Understanding different types of hair loss helps in accurate diagnosis and treatment.
October 2024 in “Journal of the Endocrine Society” Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
October 2024 in “Journal of the Endocrine Society” Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
November 2023 in “Experimental Dermatology” Exosomes from human hair follicle cells can improve aging hair follicle cell function and help regenerate hair follicles.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
222 citations
,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
148 citations
,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
139 citations
,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
138 citations
,
November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
100 citations
,
May 2011 in “Journal of Pediatric and Adolescent Gynecology” The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.
82 citations
,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
66 citations
,
February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
62 citations
,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.