146 citations
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
139 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” K6hf is a unique protein found only in a specific layer of hair follicles.
122 citations
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July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
111 citations
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March 1951 in “Annals of the New York Academy of Sciences” Understanding the mouse hair cycle is crucial for cancer research.
109 citations
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October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
98 citations
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July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
98 citations
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June 2008 in “Human mutation” A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
96 citations
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April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
95 citations
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July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
91 citations
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January 2009 in “International Journal of Trichology” Different hair evaluation methods have their own pros and cons, and using multiple methods together is best for accurate hair loss diagnosis and tracking.
Researchers developed a new model for more realistic computer graphics of hair by considering how light scatters on hair fibers.
89 citations
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September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
87 citations
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January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
86 citations
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December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
83 citations
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May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
82 citations
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May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
80 citations
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June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
75 citations
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August 2011 in “Journal of Investigative Dermatology” Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.
70 citations
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December 2004 in “Differentiation” The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
68 citations
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May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
68 citations
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August 2012 in “Journal of the American Academy of Dermatology” Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.
66 citations
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May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
66 citations
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June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
66 citations
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September 2005 in “Photochemical & photobiological sciences” We don't fully understand how sunlight damages different types of hair.
65 citations
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November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
63 citations
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October 1972 in “British Journal of Dermatology” Women with thinning hair have thinner hair strands than women without hair loss.
62 citations
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November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
62 citations
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January 2000 in “Developmental dynamics” Notch-related genes play a key role in the development and cycling of hair follicles.