May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
102 citations
,
August 2008 in “Genes & Development” Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
1 citations
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October 2022 in “Scientific reports” Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
November 2024 in “Research Square (Research Square)” Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
Human hair keratins can be turned into useful 3D biomedical scaffolds through a freeze-thaw process.
December 2025 in “Biopolymers” Heat worsens damage in chemically treated hair, especially bleached and straightened hair.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
October 2022 in “Experimental Dermatology” New technologies show promise for better hair regeneration and treatments.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
26 citations
,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
30 citations
,
February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
9 citations
,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
85 citations
,
August 2015 in “Journal of Applied Genetics” Mutations in specific genes disrupt development of sweat glands, teeth, hair, skin, and nails in HED.
5 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
November 2024 in “Burns & Trauma” Skin organoids help improve wound healing and tissue repair.
2 citations
,
June 2020 in “Journal of Investigative Dermatology” 3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
105 citations
,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
2 citations
,
January 2023 in “Applied Science and Convergence Technology” 3D bioprinting is useful for making tissues, testing drugs, and delivering drugs, but needs better materials, resolution, and scalability.
15 citations
,
July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
86 citations
,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
52 citations
,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
26 citations
,
March 2013 in “Journal of Biomedical Materials Research Part A” Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
15 citations
,
March 2012 in “International journal of nanomedicine” Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.
18 citations
,
February 2015 in “Acta Crystallographica Section D: Structural Biology” The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
51 citations
,
January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
9 citations
,
January 2021 in “International Journal of Medical Sciences” Sox10 is important for hair follicle development and hair growth cycles.
20 citations
,
May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
7 citations
,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
3 citations
,
July 2019 in “International journal of scientific research in science and technology” Herbal hair gel with fenugreek seed extract was found to increase hair growth.