8 citations
,
April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
949 citations
,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
508 citations
,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
222 citations
,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
171 citations
,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
99 citations
,
July 2005 in “Ultramicroscopy” The research improved understanding of hair and skin properties across different ethnicities and conditions.
97 citations
,
January 2005 in “Wear” Human hair and skin friction vary by ethnicity, hair type, and environmental conditions.
81 citations
,
December 2007 in “Acta materialia” AFM helped show how hair changes under tension and the effects of damage and conditioner.
73 citations
,
October 2013 in “International Journal of Cosmetic Science” Chemical hair straightening can damage hair and health, needing safer alternatives and stricter regulations.
56 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
33 citations
,
September 2012 in “Australasian Journal of Dermatology” Chemotherapy can cause hair changes similar to alopecia areata, which might lead to misdiagnosis.
31 citations
,
August 2000 in “Journal of Investigative Dermatology” Stem cells are key for hair follicle recovery.
21 citations
,
December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
14 citations
,
March 2017 in “Plastic and reconstructive surgery. Global open” Hair follicle damage happens during hair transplants and can impact success; better surgical methods are needed.
13 citations
,
April 2001 in “International Journal of Dermatology” Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.
7 citations
,
November 2006 in “Journal of immunological methods” The method can help diagnose and monitor diabetes by analyzing hair.
5 citations
,
January 2021 in “BioMed Research International” Noncrosslinked hyaluronic acid helps human hair cells grow and could be a potential hair loss treatment.
4 citations
,
January 2004 in “Biological and Pharmaceutical Bulletin” AgK114 protein helps in hamster skin injury recovery.
2 citations
,
June 2017 in “Pediatric Dermatology” A critically ill boy experienced hair loss likely due to the stress of his medical treatments, but his hair regrew completely in 1.5 months.
2 citations
,
November 2003 in “Humana Press eBooks” Hair follicle cells can help heal wounds and study skin diseases.
1 citations
,
June 2023 in “Skin Research and Technology” Hair-coating shampoos dye better initially, but hair-oxidation shampoos keep color longer and may damage hair more.
1 citations
,
January 2020 in “PubMed” Azelaic acid helps protect hair cells from UV damage and encourages hair growth by increasing certain gene expressions and proteins.
July 2025 in “International Journal of Pharmacy and Pharmaceutical Science” The herbal hair gel mask made from flaxseed, fenugreek, and rice water is safe, effective, and promotes healthy hair and scalp.
July 2024 in “Experimental Dermatology” AP collagen peptides help hair grow and improve hair health.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
November 2023 in “Hair transplant forum international” Caffeine can stimulate hair growth, but the best dose and frequency for hair loss treatment are still unknown.
January 2022 in “Food Science and Technology” The herbal mixture could potentially improve hair loss.
January 2017 in “Journal of Dermatology and Venereology” Naringenin and Hesperetin may help hair grow and protect hair cells from damage.
March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.