7 citations
,
October 2020 in “Dermatology practical & conceptual” Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.
April 2026 in “International Journal of Molecular Sciences” Wnt signaling is crucial for skin, hair, and nail health and regeneration.
77 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
11 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
26 citations
,
September 1969 in “The American journal of medicine” Cronkhite-Canada Syndrome often leads to death within 6-18 months.
1 citations
,
August 2021 Instagram ads for skin, hair, and nail supplements often make broad health claims without clear ingredient information, and are not FDA-regulated.
179 citations
,
October 2018 in “American Journal of Clinical Dermatology” Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
23 citations
,
February 1993 in “Journal of Investigative Dermatology” 15 citations
,
July 2004 in “AIDS” Indinavir therapy can cause reversible skin, hair, and nail darkening.
April 2024 in “Current research in nutrition and food science” Taking an amino acid supplement improved skin, hair, and nail health in women.
4 citations
,
August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
August 2018 in “Journal of the American Academy of Dermatology” Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
57 citations
,
February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
January 2026 in “AAPS introductions in the pharmaceutical sciences” October 1990 in “Spectrum Research Repository (Concordia University)” 1 citations
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March 2025 in “JAAD reviews.” Significant progress has been made in treating skin, hair, and nail disorders in people with skin of color, but disparities still exist.
April 2019 in “Journal of the Endocrine Society” An over-the-counter vitamin/mineral supplement improved hair loss and blood sugar control in a woman with non-classic 11-hydroxylase deficiency.
16 citations
,
February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
July 2017 in “British Journal of Dermatology” The document concludes that scalp conditions have various causes and can present in many different ways.
September 2024 in “Meditsinskiy sovet = Medical Council” Biotin effectively treats hair loss, skin, and nail issues without overdose risk.
January 1997 in “Elsevier eBooks” Hair and nails are skin parts that develop early and serve protective and functional roles.
September 2018 in “CRC Press eBooks” Hair and nail disorders can cause changes in scalp pigmentation, especially with sun exposure and alopecia.
November 2025 in “International Journal of Research in Medical Sciences” Titagen® improves skin, hair, nail health, and reduces osteoarthritis symptoms safely.
10 citations
,
January 2021 in “BioMed Research International” Some recovered COVID-19 patients experience skin, hair, and nail issues, suggesting they need follow-up care.
84 citations
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October 2005 in “Annals of Clinical Psychiatry” Hairpulling, skin picking, and nail biting cause significant harm and need more research for better treatments.
3 citations
,
February 2020 in “International journal of women’s dermatology” Most women with hair loss take more supplements than average, but these often don't help and can be risky and costly.
3 citations
,
August 2022 in “Cutis” Certain nail conditions can suggest thyroid problems, with different symptoms for underactive (slow, thin nails) and overactive (spoon-shaped, brittle nails) thyroid.
4 citations
,
March 2017 in “Journal of evolution of medical and dental sciences” Older adults often have dry skin and itching, with high blood pressure frequently linked to skin problems.
8 citations
,
April 2017 in “American Journal of Dermatopathology” Inflammation may cause nail issues in Cronkhite–Canada Syndrome.
19 citations
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October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.