10 citations
,
January 2001 in “Bioscience Biotechnology and Biochemistry” Ubiquitin, a protein, is found in hair, nails, and skin.
January 2019 in “International journal of dermatology, venereology and leprosy sciences” Patients with chronic kidney disease often have various skin problems that affect their quality of life, but early treatment can help.
11 citations
,
March 2016 in “Journal of the European Academy of Dermatology and Venereology” Almost all patients with chronic kidney disease not yet on dialysis have at least one skin problem.
June 2017 in “Journal of evolution of medical and dental sciences” About 22% of cancer patients had skin-related side effects from chemotherapy, but these were usually not severe enough to halt treatment.
36 citations
,
December 1991 in “Journal of Dermatological Science” Human nails contain both skin and hair keratins, each needing different extraction methods.
19 citations
,
October 2019 in “Dermatology Practical & Conceptual” Dermoscopy now helps diagnose various skin, hair, and nail issues, improving patient care and treatment understanding.
19 citations
,
May 2005 in “Archives of Environmental & Occupational Health” All immigrant workers in the study had skin problems, with fungal nail infections, athlete's foot, and acne or folliculitis being most common, affecting their quality of life, yet they didn't seek medical help.
6 citations
,
March 2020 in “Anais Brasileiros de Dermatologia” Thyroid disease can cause skin and hair changes, treatable with levothyroxine.
December 2025 in “Pakistan Journal of Health Sciences” Estrogen deficiency in postmenopausal women can cause skin and hair issues, but local estrogen therapies help improve vaginal health.
87 citations
,
March 2013 in “Expert Review of Anticancer Therapy” Afatinib often causes skin problems that need proactive management.
17 citations
,
January 2010 in “Acta Dermato Venereologica” EGFR inhibitors can cause yellowish skin eruptions.
16 citations
,
February 2019 in “Pediatric Blood & Cancer” Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.
10 citations
,
October 2017 in “Archivos Argentinos De Pediatria” Most hospitalized children with skin issues were boys, with allergic skin diseases like atopic dermatitis being most common, and treatments were usually topical.
5 citations
,
January 2021 in “Dermatology Online Journal” An 84-year-old man developed a rare scalp condition from a cancer drug but continued treatment as it was otherwise well tolerated.
2 citations
,
February 2021 in “PubMed” Koilonychia in alopecia areata can improve with oral corticosteroids.
2 citations
,
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” A TP63 gene mutation causes significant hair loss and mild skin, nail, and tooth abnormalities.
December 2025 in “International Journal of Clinical Medical Research” Diet and gut health can improve skin, hair, and nails.
July 2022 in “Clinical dermatology review” Most patients with chronic kidney disease had skin issues like paleness and dry skin, and treating these can improve their lives.
New cancer drugs can cause skin side effects like rashes, dry skin, hair changes, and nail problems.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Intermittent isotretinoin can cause various skin, hair, and nail changes.
141 citations
,
September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
1 citations
,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
55 citations
,
November 2004 in “Expert opinion on drug safety” Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.
44 citations
,
August 2010 in “Lupus” Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.
25 citations
,
January 2011 in “Annals of Dermatology” Erlotinib can cause hair loss as a side effect.
71 citations
,
February 2012 in “The American Journal of Human Genetics” A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.
53 citations
,
May 2001 in “The American journal of the medical sciences” Chemotherapy can cause various skin problems, and recognizing them helps improve patient care.
41 citations
,
October 2017 in “International Journal of Women's Dermatology” Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.
36 citations
,
January 2000 in “British journal of dermatology/British journal of dermatology, Supplement” A mother and daughter had severe skin, hair, and eye issues linked to IFAP.
22 citations
,
January 2009 in “Advances in experimental medicine and biology” FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.