Skin stem cells in hair follicles are important for touch sensation.
September 2017 in “Journal of Investigative Dermatology” Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
March 2017 in “Trichology and cosmetology:” Psoriasis treatment may affect body hair growth, with a complex relationship between skin and hair growth mechanisms.
September 2016 in “Journal of Dermatological Science” Hair follicle stem cells can become heart muscle cells.
September 2016 in “British Journal of Dermatology” The document discusses new cosmetic dermatology technologies, safety, robotic hair restoration, and upcoming courses on genomics and skin cancer management.
August 2016 in “Journal of Investigative Dermatology” Activating Nrf2 can improve wound healing by increasing hair follicle stem cells.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
October 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF9 from certain T cells helps create new hair follicles during wound healing, which could potentially be used for hair loss treatments.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
Somatostatin helps hair follicles suppress immune responses, which might aid in treating certain hair loss conditions.
September 2001 in “Connective tissue” Type XII and XIV collagens help maintain hair follicle structure in bovine skin.
54 citations
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January 2013 in “Journal of Biological Macromolecules” A new method effectively separates keratin-associated proteins and keratin from human hair.
43 citations
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August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
1 citations
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January 2020 in “Indian Dermatology Online Journal” Pigtail hair is a sign of new hair growth and should be recognized in hair loss conditions like acute telogen effluvium.
February 2026 in “Biochemical and Biophysical Research Communications” Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
70 citations
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February 2007 in “Journal of Investigative Dermatology” K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
51 citations
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May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
26 citations
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October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
23 citations
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June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
17 citations
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October 2015 in “Medicine and Pharmacy Reports” Animal models are crucial for learning about hair loss and finding treatments.
17 citations
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May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
12 citations
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December 1985 in “Dicp-The annals of pharmacotherapy” Carbamazepine can cause hair loss, which may reverse when the medication is stopped.
6 citations
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July 1975 in “Archives of Dermatology” Rapid weight loss from dieting and hormonal injections can cause significant hair loss in women.
1 citations
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June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Reprogramming 3D environments can create hair follicles in the lab.
1 citations
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July 2015 in “The European research journal” Stopping aripiprazole can reverse its side effect of hair loss.
1 citations
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July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
March 2025 in “International Journal of Molecular Sciences” Veratric Acid may help promote hair growth and reduce hair loss.
June 2026 in “Research Square” The study highlights the crucial role of THBS4 in hair regeneration by modulating the mechanical properties of the dermal niche, which reduces matrix stiffness and enhances interactions between the epidermis and dermis. This process activates hair follicle stem cells (HFSCs) and accelerates the transition from the telogen to anagen phase, promoting hair growth. THBS4 upregulation in dermal fibroblasts activates signaling pathways involving ITGB1, EGR1, and HMGCR, facilitating HFSC proliferation. Experiments with mice and organoids showed that THBS4 treatment significantly enhances hair regeneration, suggesting its potential as a therapeutic target for hair loss treatments. Further research is needed to explore the detailed mechanisms of THBS4 in extracellular matrix assembly and metabolic reprogramming.
March 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The dermal sheath's contraction is crucial for hair follicle regression and stem cell relocation.
January 2019 in “Durham e-Theses (Durham University)” Advanced microscopy shows hair damage and keratin proteins' roles, aiding future cosmetic treatments.