research Hirsutism: Diagnosis and management
The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
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research The modern management of hirsutism
Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
research Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
research Oral Supplementation of Nicotinamide Mononucleotide (NMN) Improves Hair Quality and Subjective Perception of Hair Appearance in Middle-Aged Women
NMN supplements may improve hair quality and appearance in middle-aged women.
research Whether the transient hair shedding phase exist after minoxidil treatment and does it predict treatment efficacy? A retrospective study in androgenetic alopecia patients
Temporary hair shedding after minoxidil use may indicate effective treatment.
research Lactiplantibacillus plantarum subsp. plantarum N793 株含有ローションの頭皮への塗布による薄毛に悩む男女の毛髪に及ぼす影響
The lotion with N793 strain significantly increased hair density and reduced hair loss safely.
research Androgenetic alopecia—Perspective from patients in a Singaporean tertiary Dermatology center
Hair loss affects self-esteem; patients seek effective, low side-effect treatments.
research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations
Plucking some hairs can trigger nearby unplucked hairs to grow back more due to a collective response.
research Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration
Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
research Hairy tale of signaling in hair follicle development and cycling
Hair growth and development are controlled by specific signaling pathways.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Biology of the wool follicle: an excursion into a unique tissue interaction system waiting to be re‐discovered
The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
research The structure of people’s hair
Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
research Chemotherapy-induced alopecia
Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
research Diagnosis and management of the dermatologic manifestations of the polycystic ovary syndrome
The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
research Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle
EGF controls hair growth by regulating hair follicles' growth phases.
research The Cytology and Cytochemistry of the Wool Follicle
Wool follicles are complex, involving interactions between different cell types and structures.
research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression
Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
research Hair removal by lasers and intense pulsed light sources
Lasers and intense pulsed light can safely and effectively remove hair by targeting hair follicles.
research Trichotillomania
Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.
research What causes hidradenitis suppurativa ?—15 years after
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research Outcome of long-term treatment with the 5α-reductase inhibitor finasteride in idiopathic hirsutism: clinical and hormonal effects during a 1-year course of therapy and 1-year follow-up
Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
research Replicative stress, stem cells and aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
research Telogen effluvium
Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
research Approach to the adult female patient with diffuse nonscarring alopecia
The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.