232 citations
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October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
Growing hair follicles from cultured cells could potentially treat baldness, but more research is needed.
January 2009 in “Indian Journal of Plastic Surgery” Surgical methods for hair loss due to scarring should be chosen based on the size, location, and shape of the area, with most patients seeing good results.
133 citations
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
99 citations
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January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
43 citations
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January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
38 citations
,
February 2016 in “Surgery Journal” Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
1 citations
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December 2006 in “Burns” New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.
August 2025 in “Plastic and Aesthetic Research” Microneedling can effectively treat hair loss and works well with other treatments, but more research is needed.
July 2025 in “Bioactive Materials” New engineering methods show promise for regenerating hair follicles using stem cells and advanced technologies.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Surgical treatments for vitiligo are safe and effective for some patients.
January 2024 in “ACS Biomaterials Science & Engineering” A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
May 2023 in “Aesthetic Plastic Surgery” The document concludes that there are various surgical techniques for hair restoration, their success depends on the surgeon's skill, patient's health, and quality of donor hair, and they can potentially improve the mental well-being of those with hair loss.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
320 citations
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December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
202 citations
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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
20 citations
,
September 2015 in “Protein expression and purification” Scientists made safflower seeds produce a human growth factor that could help with hair growth and wound healing.
6 citations
,
July 2025 in “Advanced Materials” Biomimetic cell membrane-coated scaffolds significantly enhance tissue regeneration by mimicking natural cellular environments.
3 citations
,
August 2011 in “InTech eBooks” The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
15 citations
,
September 2018 in “Applied Biological Chemistry” Matrigel supports cell growth and repair, and thymosin beta 4 aids tissue regeneration and healing.
5 citations
,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
10 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
3 citations
,
February 1996 in “Dermatologic Surgery” Walter P. Unger suggests using advanced hair transplant techniques for broader coverage, as they provide natural results and use donor tissue efficiently, while also recommending personalized planning due to the unpredictable progression of baldness.
24 citations
,
April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
48 citations
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February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
14 citations
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May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.